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Bcl-2 Rabbit mAb (A19693)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Western blot analysis of various lysates using Bcl-2 Rabbit mAb (A19693) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.

ABclonal:Immunohistochemistry - Bcl-2 Rabbit mAb (A19693)

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Bcl-2 Rabbit mAb (A19693) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Human follicular lymphoma using Bcl-2 Rabbit mAb (A19693) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Human appendix using Bcl-2 Rabbit mAb (A19693) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

ABclonal:Immunoprecipitation - Bcl-2 Rabbit mAb (A19693)

Immunoprecipitation analysis of 200 μg extracts of Mouse lung using 3 μg Bcl-2 antibody (A19693). Western blot was performed from the immunoprecipitate using Bcl-2 antibody (A19693) at a dilution of 1:1000.

Review

Overview

Product name	Bcl-2 Rabbit mAb
Catalog No.	A19693
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC0173

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human Bcl-2 (P10415).
Sequence	MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFD
Gene ID
Swiss Prot
Synonyms	Bcl-2; PPP1R50
Calculated MW	26kDa
Observed MW	26kDa

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:1000 - 1:2000 IHC-P 1:1000 - 1:4000 IP 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry Immunoprecipitation
Positive samples	293T, Mouse testis, Mouse lung
Cellular location	Cytoplasm, Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein.
Customer validation	(Human Fibroblast Cell ) WB(Mus musculus, Sanghuangporus vaninii, Homo sapiens, Rattus norvegicus, Gallus gallus, Fathead minnow, Dianella ensifolia, Mus musculus, Other, Rattus norvegicus, Capra hircus) IHC(Homo sapiens, Mus musculus) IHC(Homo sapiens, Rattus norvegicus, Capra hircus) IF(Mus musculus) IP(Mus musculus) WB(Mus musculus)

Documents

Certificate of Compliance

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Lot number

Research Area

Bcl-2 Rabbit mAb images

Western blot - Bcl-2 Rabbit mAb (A19693)

Immunohistochemistry - Bcl-2 Rabbit mAb (A19693)

Immunoprecipitation - Bcl-2 Rabbit mAb (A19693)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A19693

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Reviews List

Product Protocols

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Int Immunopharmacol

Application:

IF:

4.93

Species:

Mus musculus

PMID:

34358859

Title:

Methyl eugenol attenuates liver ischemia reperfusion injury via activating PI3KAkt signaling

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Int J Biol Macromol

Application:

IF:

6.953

Species:

Sanghuangporus vaninii

PMID:

32629056

Title:

Characterization of a polysaccharide from Sanghuangporus vaninii and its antitumor regulation via activation of the p53 signaling pathway in breast cancer MCF-7 …

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

ACS Omega

Application:

IF:

3.512

Species:

Homo sapiens

PMID:

33644550

Title:

Amlexanox Enhances Temozolomide-Induced Antitumor Effects in Human Glioblastoma Cells by Inhibiting IKBKE and the Akt-mTOR Signaling Pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Food Chem Toxicol

Application:

IF:

6.02

Species:

Mus musculus

PMID:

34600025

Title:

Prenatal EGCG exposure-induced heart mass reduction in adult male mice and underlying mechanisms

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

J Sport Health Sci

Application:

IF:

7.179

Species:

Mus musculus

PMID:

34116237

Title:

Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Exp Ther Med

Application:

IF:

2.447

Species:

Mus musculus

PMID:

34194560

Title:

Protective effects of miR?155?5p silencing on IFN?γ?induced apoptosis and inflammation in salivary gland epithelial cells

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Eur J Pharmacol

Application:

IF:

4.432

Species:

Rattus norvegicus

PMID:

34280397

Title:

Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4 0

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomed Pharmacother

Application:

IF:

6.529

Species:

Mus musculus

PMID:

34649218

Title:

Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Int Immunopharmacol

Application:

IF:

4.932

Species:

Rattus norvegicus

PMID:

34537481

Title:

6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1/FAF1 complex dissociation-mediated autophagy

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomedicines

Application:

IF:

6.081

Species:

Mus musculus

PMID:

34572430

Title:

RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Neuroscience

Application:

IF:

3.7

Species:

Rattus norvegicus

PMID:

36067951

Title:

Inhibition of miR-423-5p exerts neuroprotective effects in an experimental rat model of cerebral ischemia/reperfusion injury

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Frontiers in immunology

Application:

IF:

8.78

Species:

Gallus gallus

PMID:

35833119

Title:

Lnc90386 Sponges miR-33-5p to Mediate Mycoplasma gallisepticum-Induced Inflammation and Apoptosis in Chickens via the JNK Pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Antioxidants (Basel, Switzerland)

Application:

IF:

7.67

Species:

Homo sapiens

PMID:

36139869

Title:

DHPA Protects SH-SY5Y Cells from Oxidative Stress-Induced Apoptosis via Mitochondria Apoptosis and the Keap1/Nrf2/HO-1 Signaling Pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Materials today. Bio

Application:

IF:

10.76

Species:

Mus musculus

PMID:

36176720

Title:

Ignored role of polyphenol in boosting reactive oxygen species generation for polyphenol/chemodynamic combination therapy - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Evidence-based complementary and alternative medicine : eCAM

Application:

IF:

2.65

Species:

Mus musculus

PMID:

35747379

Title:

Renal Protective Mechanisms of Shenyuan Particle in Db/Db Mice: A Study Based on Network Pharmacology - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Toxicology

Application:

IF:

4.57

Species:

Homo sapiens

PMID:

36243239

Title:

Maternal exposure to PM2. 5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Frontiers in pharmacology

Application:

IHC

IF:

5.98

Species:

Homo sapiens

PMID:

36120368

Title:

Protective effects of menthol against sepsis-induced hepatic injury: Role of mediators of hepatic inflammation, apoptosis, and regeneration - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Frontiers in endocrinology

Application:

IF:

6.05

Species:

Mus musculus

PMID:

36237185

Title:

Hyperinsulinemia impairs the metabolic switch to ketone body utilization in proximal renal tubular epithelial cells under energy crisis via the inhibition of the SIRT3/SMCT1 pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

Application:

IF:

2.27

Species:

Mus musculus

PMID:

36592742

Title:

NeiyiKangfu tablets control the progression of endometriosis through inhibiting RAF/MEK/ERK signal pathway by targeting RKIP

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Veterinary research

Application:

IF:

3.82

Species:

Gallus gallus

PMID:

36471418

Title:

Mycoplasma gallisepticum escapes the host immune response via gga-miR-365-3p/SOCS5/STATs axis - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of agricultural and food chemistry

Application:

IF:

5.89

Species:

Gallus gallus

PMID:

35128924

Title:

Glycyrrhizic Acid against Mycoplasma gallisepticum-Induced Inflammation and Apoptosis Through Suppressing the MAPK Pathway in Chickens

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Homo sapiens

PMID:

36430694

Title:

Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biochemical pharmacology

Application:

IF:

6.1

Species:

Mus musculus

PMID:

36720354

Title:

Aucubin protects mouse cochlear hair cells from cisplatin-induced ototoxicity via activation of the PI3K/AKT/STAT3 pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Frontiers in immunology

Application:

IF:

8.78

Species:

Mus musculus

PMID:

36713420

Title:

CTSB promotes sepsis-induced acute kidney injury through activating mitochondrial apoptosis pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Food & function

Application:

IF:

6.31

Species:

Homo sapiens

PMID:

36762489

Title:

Latex Derived from Ficus carica L. Inhibited the Growth of NSCLC by Regulating the Caspase/Gasdermin/AKT Signaling Pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cancers

Application:

IF:

6.57

Species:

Homo sapiens

PMID:

36900408

Title:

Sodium New Houttuyfonate Induces Apoptosis of Breast Cancer Cells via ROS/PDK1/AKT/GSK3β Axis - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

The American journal of Chinese medicine

Application:

IF:

Species:

Rattus norvegicus

PMID:

36472847

Title:

Curdione Relieved Isoproterenol-Induced Myocardial Damage through Inhibiting Oxidative Stress and Apoptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Food & function

Application:

IF:

6.31

Species:

Mus musculus

PMID:

36786681

Title:

Confusoside, a dihydrochalcone glucoside, prevents acetaminophen-induced liver injury by modulating the Keap1-Nrf2/Nf-κB/Caspase signaling pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Heliyon

Application:

IF:

3.77

Species:

Mus musculus

PMID:

37131441

Title:

miR-21-5p prevents doxorubicin-induced cardiomyopathy by downregulating BTG2 - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Thoracic cancer

Application:

IF:

3.22

Species:

Homo sapiens

PMID:

36919755

Title:

UHMK1 promotes lung adenocarcinoma oncogenesis by regulating the PI3K/AKT/mTOR signaling pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

7.41

Species:

Homo sapiens

PMID:

37001180

Title:

Garcinone E triggers apoptosis and cell cycle arrest in human colorectal cancer cells by mediating a reactive oxygen species–dependent JNK signaling …

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Scientific reports

Application:

IF:

4.99

Species:

Homo sapiens

PMID:

37217794

Title:

LncRNA FAS-AS1 upregulated by its genetic variation rs6586163 promotes cell apoptosis in nasopharyngeal carcinoma through regulating mitochondria function and Fas splicing - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Nature communications

Application:

IF:

17.69

Species:

Mus musculus

PMID:

37723159

Title:

Discovery of the major 15-30 nt mammalian small RNAs, their biogenesis and function - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Heliyon

Application:

IF:

3.77

Species:

Rattus norvegicus

PMID:

37662743

Title:

Rosemarinic acid protects -cell from STZ-induced cell damage via modulating NF- pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Neuroreport

Application:

IF:

1.7

Species:

Rattus norvegicus

PMID:

37851367

Title:

Total flavonoids of Cynomorium songaricum attenuates cognitive defects in an A1-42-induced Alzheimers disease rat model by activating BDNF/TrkB signaling transduction - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Application:

IF:

17.52

Species:

Homo sapiens

PMID:

37705061

Title:

TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

Application:

IF:

2.9

Species:

Homo sapiens

PMID:

37878884

Title:

Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Nature communications

Application:

IF:

17.69

Species:

Homo sapiens

PMID:

37932306

Title:

Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International immunopharmacology

Application:

IF:

5.71

Species:

Gallus gallus

PMID:

37717315

Title:

Avian safety guardian: Luteolin restores Mycoplasma gallisepticum-induced immunocompromise to improve production performance via inhibiting the IL-17/NF-kB

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International immunopharmacology

Application:

IF:

5.71

Species:

Mus musculus

PMID:

37913569

Title:

Caffeic acid modulates activation of neutrophils and attenuates sepsis-induced organ injury by inhibiting 5-LOX/LTB4 pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International immunopharmacology

Application:

IF:

5.71

Species:

Mus musculus

PMID:

37879229

Title:

Polo-like kinase 1 promotes sepsis-induced myocardial dysfunction

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Fish & shellfish immunology

Application:

IF:

4.62

Species:

Fathead minnow

PMID:

37661036

Title:

Chlorpyrifos-mediated mitochondrial calcium overload induces EPC cell apoptosis via ROS/AMPK/ULK1

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Experimental cell research

Application:

IF:

4.14

Species:

Homo sapiens

PMID:

37742725

Title:

Emodin derivative E35 and its combination with autophagy inhibitor against acute myeloid leukemia cells in vitro and in vivo

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Aging

Application:

IF:

5.95

Species:

Homo sapiens

PMID:

37851362

Title:

Triptolide inhibits epithelial ovarian tumor growth by blocking the hedgehog/Gli pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

ACS applied materials & interfaces

Application:

IHC

IF:

10.38

Species:

Mus musculus

PMID:

38157479

Title:

Mucoadhesive Carrier-Mediated Oral Co-delivery of Bcl2 Inhibitors Improves Gastric Cancer Treatment

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of Cancer

Application:

IF:

4.47

Species:

Dianella ensifolia,Homo sapiens

PMID:

38164280

Title:

Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Tissue Cell

Application:

IF:

2.586

Species:

Homo sapiens

PMID:

34666282

Title:

ATF3 regulates oxidative stress and extracellular matrix degradation via p38/Nrf2 signaling pathway in pelvic organ prolapse

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Molecular therapy : the journal of the American Society of Gene Therapy

Application:

WB, IHC

IF:

12.91

Species:

Homo sapiens

PMID:

36307991

Title:

N6-methyladenosine demethylase FTO enhances chemo-resistance in colorectal cancer through SIVA1-mediated apoptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Autophagy

Application:

IF:

13.39

Species:

Homo sapiens

PMID:

36300799

Title:

A/(H1N1) pdm09 NS1 promotes viral replication by enhancing autophagy through hijacking the IAV negative regulatory factor LRPPRC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

The Journal of biological chemistry

Application:

IF:

Species:

Homo sapiens

PMID:

36736423

Title:

Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Experimental cell research

Application:

IF:

4.14

Species:

Mus musculus

PMID:

37926343

Title:

Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cellular signalling

Application:

IF:

4.85

Species:

Homo sapiens

PMID:

38040402

Title:

Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cellular Signalling

Application:

IF:

4.8

Species:

Homo sapiens

PMID:

36473621

Title:

DHCR7 promotes tumorigenesis via activating PI3K/AKT/mTOR signalling pathway in bladder cancer

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Chinese journal of integrative medicine

Application:

IF:

2.62

Species:

Homo sapiens

PMID:

37076638

Title:

Asperuloside Promotes Apoptosis of Cervical Cancer Cells through Endoplasmic Reticulum Stress-Mitochondrial Pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biochemical pharmacology

Application:

IF:

6.1

Species:

Homo sapiens

PMID:

37778447

Title:

Galectin-7 promotes cisplatin efficacy by facilitating apoptosis and G3BP1 degradation in cervical cancer

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biochemical pharmacology

Application:

IF:

6.1

Species:

Homo sapiens

PMID:

37290598

Title:

Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Mus musculus

PMID:

38139216

Title:

Molecular Mechanism of the Asarum-Angelica Drug Pair in the Treatment of Periodontitis Based on Network Pharmacology and Experimental Verification - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Hematology (Amsterdam, Netherlands)

Application:

IF:

2.26

Species:

Homo sapiens

PMID:

37014739

Title:

miR-100-5p is upregulated in multiple myeloma and involves in the pathogenesis of multiple myeloma through targeting MTMR3

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cancer cell international

Application:

IF:

6.429

Species:

Homo sapiens, Mus musculus

PMID:

35277179

Title:

High PPT1 expression predicts poor clinical outcome and PPT1 inhibitor DC661 enhances sorafenib sensitivity in hepatocellular carcinoma

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

BMC complementary medicine and therapies

Application:

IF:

2.83

Species:

Homo sapiens

PMID:

38297292

Title:

Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cell death & disease

Application:

IF:

Species:

Homo sapiens

PMID:

38238320

Title:

Non-alcoholic fatty liver disease promotes breast cancer progression through upregulated hepatic fibroblast growth factor 21 - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of translational medicine

Application:

IF:

8.44

Species:

Mus musculus

PMID:

38368334

Title:

Engineered bone marrow mesenchymal stem cell-derived exosomes loaded with miR302 through the cardiomyocyte specific peptide can reduce myocardial

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomedicines

Application:

IF:

4.75

Species:

Other

PMID:

38137377

Title:

Tephrosin Suppresses the Chemoresistance of Paclitaxel-Resistant Ovarian Cancer via Inhibition of FGFR1 Signaling Pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Molecules (Basel, Switzerland)

Application:

IF:

4.92

Species:

Homo sapiens

PMID:

38202856

Title:

Pan-EGFR Inhibitor Dacomitinib Resensitizes Paclitaxel and Induces Apoptosis via Elevating Intracellular ROS Levels in Ovarian Cancer SKOV3-TR Cells - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Molecular medicine (Cambridge, Mass.)

Application:

IF:

5.7

Species:

Rattus norvegicus

PMID:

38395742

Title:

WSB1, as an E3 ligase, restrains myocardial ischemia-reperfusion injury by activating -catenin signaling via promoting GSK3 ubiquitination - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Frontiers in pharmacology

Application:

IF:

5.6

Species:

Homo sapiens

PMID:

38410130

Title:

Discovery of a small-molecule NDR1 agonist for prostate cancer therapy - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Molecular carcinogenesis

Application:

IF:

4.6

Species:

Homo sapiens

PMID:

38289159

Title:

Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF1/Psmad3 signaling through HIF1a

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cells

Application:

IF:

7.666

Species:

Mus musculus

PMID:

34440873

Title:

miR-135a Suppresses Granulosa Cell Growth by Targeting Tgfbr1 and Ccnd2 during Folliculogenesis in Mice

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Application:

IF:

22.84

Species:

Homo sapiens

PMID:

37230023

Title:

GATA3 mediates doxorubicin resistance by inhibiting CYB5R2-catalyzed iron reduction in breast cancer cells

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Homo sapiens, Rattus norvegicus

PMID:

36613500

Title:

Changes in the Expression and Functional Activities of C-X-C Motif Chemokine Ligand 13 (CXCL13) in Hyperplastic Prostate - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Molecular nutrition & food research

Application:

IHC

IF:

6.57

Species:

Mus musculus

PMID:

37057609

Title:

Icariin ameliorates spermatogenesis disorder in obese mice induced by highfat diet through regulating the glycolytic pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Am J Transl Res

Application:

IF:

3.94

Species:

Mus musculus

PMID:

33437388

Title:

Methyl-CpG-binding domain 3 (Mbd3) is an important regulator for apoptosis in mouse embryonic stem cells

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Theranostics

Application:

IHC, IF

IF:

11.6

Species:

Mus musculus

PMID:

35910796

Title:

Inhibition of acylglycerol kinase sensitizes DLBCL to venetoclax via upregulation of FOXO1-mediated BCL-2 expression - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Experimental animals

Application:

IF:

1.79

Species:

Rattus norvegicus

PMID:

36927982

Title:

Knockdown of HDAC9 attenuates sepsis-induced myocardial injury and inflammatory response

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Toxics

Application:

IF:

4.47

Species:

Mus musculus

PMID:

36976996

Title:

Spleen Toxicity of Organophosphorus Flame Retardant TDCPP in Mice and the Related Mechanisms - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cells

Application:

IF:

7.66

Species:

Homo sapiens

PMID:

36429034

Title:

LTB4R Promotes the Occurrence and Progression of Clear Cell Renal Cell Carcinoma (ccRCC) by Regulating the AKT/mTOR Signaling Pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International immunopharmacology

Application:

WB, IHC

IF:

5.71

Species:

Rattus norvegicus

PMID:

36274486

Title:

Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Phytomedicine : international journal of phytotherapy and phytopharmacology

Application:

IF:

6.65

Species:

Homo sapiens

PMID:

37269775

Title:

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Naunyn-Schmiedeberg's archives of pharmacology

Application:

IF:

3.6

Species:

Mus musculus

PMID:

38498061

Title:

Identification of Dalbergiae Odoriferae Lignum active ingredients and potential mechanisms in the treatment of adriamycin-induced cardiotoxicity based on network

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

7.41

Species:

Mus musculus

PMID:

37783150

Title:

Angelica sinensis polysaccharides ameliorated 5-Fluorouracil-induced damage of early B cell progenitors by alleviating oxidative stress of IL-7 producing

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Toxicon : official journal of the International Society on Toxinology

Application:

IF:

2.8

Species:

Rattus norvegicus

PMID:

38519012

Title:

Protective effect of ginsenoside Rb1 against aconitine cardiotoxicity studied by myocardial injury, action potential, and calcium signaling

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

PloS one

Application:

IF:

3.7

Species:

Rattus norvegicus

PMID:

38568919

Title:

AP39, a novel mitochondria-targeted hydrogen sulfide donor ameliorates doxorubicin-induced cardiotoxicity by regulating the AMPK/UCP2 pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Translational research : the journal of laboratory and clinical medicine

Application:

IP, WB

IF:

7.8

Species:

Mus musculus

PMID:

38494125

Title:

Genetic and pharmacological targeting of XBP1 alleviates hepatic ischemia reperfusion injury by enhancing FoxO1-dependent mitophagy

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

MedComm

Application:

IF:

9.9

Species:

Homo sapiens

PMID:

38706741

Title:

Tryptophan deficiency induced by indoleamine 2,3-dioxygenase 1 results in glucose transporter 1-dependent promotion of aerobic glycolysis in pancreatic cancer - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Theriogenology

Application:

WB, IHC

IF:

2.92

Species:

Capra hircus

PMID:

37944429

Title:

Autophagic and apoptotic proteins in goat corpus luteum and the effect of Adiponectin/AdipoRon on luteal cell autophagy and apoptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Adipocyte

Application:

WB, IHC

IF:

3.55

Species:

Homo sapiens

PMID:

37993991

Title:

Ojeok-san enhances platinum sensitivity in ovarian cancer by regulating adipocyte paracrine IGF1 secretion

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

American journal of cancer research

Application:

IF:

5.3

Species:

Homo sapiens

PMID:

38590396

Title:

Endogenous S100P-mediated autophagy regulates the chemosensitivity of leukemia cells through the p53/AMPK/mTOR pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cancer biomarkers : section A of Disease markers

Application:

IF:

3.1

Species:

Homo sapiens

PMID:

38250761

Title:

GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Open medicine (Warsaw, Poland)

Application:

IF:

Species:

Mus musculus

PMID:

38756247

Title:

HOXD10 regulates intestinal permeability and inhibits inflammation of dextran sulfate sodium-induced ulcerative colitis through the inactivation of the Rho/ROCK/MMPs axis - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

ACS central science

Application:

IF:

18.2

Species:

Homo sapiens

PMID:

38799671

Title:

O-GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Renal failure

Application:

IF:

Species:

Mus musculus

PMID:

38856314

Title:

H-151 attenuates lipopolysaccharide-induced acute kidney injury by inhibiting the STING-TBK1 pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biochemical and biophysical research communications

Application:

IF:

3.1

Species:

Homo sapiens

PMID:

38484574

Title:

Identification of HK3 as a promising immunomodulatory and prognostic target in sepsis-induced acute lung injury

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Oncogene

Application:

IF:

Species:

Homo sapiens

PMID:

38783100

Title:

tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Clinical, cosmetic and investigational dermatology

Application:

IF:

2.3

Species:

Homo sapiens

PMID:

38911338

Title:

Integrated Analysis Reveals COL4A3 as a Novel Diagnostic and Therapeutic Target in UV-Related Skin Cutaneous Melanoma - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Biomacromolecules

Application:

IF:

6.2

Species:

Mus musculus

PMID:

38779908

Title:

Paclitaxel Overload Supramolecular Oxidative Stress Nanoamplifier with a CDK12 Inhibitor for Enhanced Cancer Therapy

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of radiation research

Application:

IF:

Species:

Homo sapiens

PMID:

38682896

Title:

A recombinant plasmid encoding human hepatocyte growth factor promotes healing of combined radiation-trauma skin injury involved in regulating Nrf2 pathway in

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Cellular oncology (Dordrecht)

Application:

IF:

6.6

Species:

Mus musculus

PMID:

38954215

Title:

Suppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

The American journal of Chinese medicine

Application:

IF:

5.7

Species:

Rattus norvegicus

PMID:

38716618

Title:

Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Heliyon

Application:

IF:

Species:

Other

PMID:

38933967

Title:

Ginsenoside Rd reduces cell proliferation of non-small cell lung cancer cells by p53-mitochondrial apoptotic pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Mycotoxin research

Application:

IF:

Species:

Homo sapiens

PMID:

38913091

Title:

Baicalin attenuates aflatoxin B1-induced hepatotoxicity via suppressing c-Jun-N-terminal kinase-mediated cell apoptosis

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of the American Heart Association

Application:

IF:

5.4

Species:

Rattus norvegicus

PMID:

38934856

Title:

miR193b3p and miR346 Exert Antihypertensive Effects in the Rostral Ventrolateral Medulla

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

BMC cardiovascular disorders

Application:

IF:

2.1

Species:

Mus musculus

PMID:

39098896

Title:

RING finger protein 5 protects against acute myocardial infarction by inhibiting ASK1 - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Ecotoxicology and environmental safety

Application:

IF:

6.8

Species:

Homo sapiens

PMID:

38944012

Title:

The combined effects of polystyrene of different sizes and cadmium in mouse kidney tissues

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Clinical epigenetics

Application:

IF:

5.7

Species:

Mus musculus

PMID:

39014511

Title:

H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Pesticide biochemistry and physiology

Application:

IF:

4.7

Species:

Mus musculus

PMID:

39084803

Title:

Thiram exposure: Disruption of the blood-testis barrier and altered apoptosis-autophagy dynamics in testicular cells via the Bcl-2/Bax and mTOR/Atg5/p62 pathways in

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Bioorganic chemistry

Application:

IF:

5.1

Species:

Other

PMID:

38772289

Title:

Design, synthesis, biological evaluation of novel piperidine-based derivatives as potent poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.4

Species:

Mus musculus

PMID:

38823659

Title:

Safranal alleviates pentetrazole-induced epileptic seizures in mice by inhibiting the NF-B signaling pathway and mitochondrial-dependent apoptosis through GSK-3

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Oncology letters

Application:

IF:

2.9

Species:

Homo sapiens

PMID:

37205919

Title:

1,4,5,6,7,8-Hexahydropyrido[4,3-d]pyrimidine inhibits HepG2 cell proliferation, migration and invasion, and induces apoptosis through the upregulation of miR-26b-5p by targeting CDK8 - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Theranostics

Application:

IF:

12.4

Species:

Homo sapiens, Mus musculus

PMID:

33391463

Title:

LT-171-861, a novel FLT3 inhibitor, shows excellent preclinical efficacy for the treatment of FLT3 mutant acute myeloid leukemia

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Journal of inflammation research

Application:

IF:

4.5

Species:

Mus musculus

PMID:

39380664

Title:

Mangiferin Ameliorates CCl4-Triggered Acute Liver Injury by Inhibiting Inflammatory Response and Oxidative Stress: Involving the Nrf2-ARE Pathway - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Bioorganic chemistry

Application:

IF:

5.1

Species:

Homo sapiens

PMID:

38735265

Title:

Biological impact and therapeutic potential of a novel camptothecin derivative (FLQY2) in pancreatic cancer through inactivation of the PDK1/AKT/mTOR pathway

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

International journal of cardiology

Application:

IF:

3.5

Species:

Mus musculus

PMID:

38723908

Title:

USP7 cardiomyocyte specific knockout causes disordered mitochondrial biogenesis and dynamics and early neonatal lethality in mice

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

Heliyon

Application:

IF:

Species:

Homo sapiens

PMID:

39258188

Title:

Pharmaceutical inhibition of BCL6 ameliorates resistance to imatinib in chronic myeloid leukemia - PMC

References for Bcl-2 Rabbit mAb (A19693)

Product:

Bcl-2 Rabbit mAb

Journal:

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Application:

IF:

4.8

Species:

Rattus norvegicus

PMID:

38050647

Title:

GRP78 improves the therapeutic effect of mesenchymal stem cells on hemorrhagic shockinduced liver injury: Involvement of the NFB and HO1/Nrf2 pathways