제품 > 항체 > 다중클론항체(pAb)

JNK1 Rabbit pAb (A0288)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Western blot analysis of lysates from SH-SY5Y cells, using JNK1 Rabbit pAb (A0288) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.

Western blot analysis of various lysates using JNK1 Rabbit pAb (A0288) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 180s.

ABclonal:Immunohistochemistry - JNK1 Rabbit pAb (A0288)

Immunohistochemistry analysis of paraffin-embedded rat pancreas using JNK1 Rabbit pAb (A0288) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded human thyroid cancer using JNK1 Rabbit pAb (A0288) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

ABclonal:Immunofluorescence - JNK1 Rabbit pAb (A0288)

Immunofluorescence analysis of HeLa cells using JNK1 Rabbit pAb (A0288) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Review

Overview

Product name	JNK1 Rabbit pAb
Catalog No.	A0288
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 245-345 of human JNK1 (NP_620635.1).
Sequence	CPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDER
Gene ID
Swiss Prot
Synonyms	JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Calculated MW	48kDa
Observed MW	44kDa

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 IHC-P 1:50 - 1:200 IF/ICC 1:50 - 1:200
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry Immunofluorescence
Positive samples	SH-SY5Y, Mouse kidney, Rat heart
Cellular location	Cytoplasm, Nucleus
Customer validation	(Mouse heart tissue) WB(Rattus norvegicus, Homo sapiens, Mus musculus, Bos taurus, Chlorocebus aethiops, Gallus gallus, Mus musculus, Rattus norvegicus, Bos taurus, Homo sapiens) IF(Mus musculus, Ctenopharyngodon idella) IHC(Mus musculus) qPCR(Homo sapiens) WB(Homo sapiens)

Documents

Certificate of Compliance

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Lot number

Research Area

JNK1 Rabbit pAb images

Western blot - JNK1 Rabbit pAb (A0288)

Immunohistochemistry - JNK1 Rabbit pAb (A0288)

Immunofluorescence - JNK1 Rabbit pAb (A0288)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A0288

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Reviews List

Product Protocols

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Scientific Reports

Application:

IF:

4.379

Species:

Rattus norvegicus

PMID:

26603550

Title:

Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Application:

IF:

5.293

Species:

Homo sapiens

PMID:

28680855

Title:

p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

International Journal Of Biochemistry & Cell Biology

Application:

IF:

5.085

Species:

Mus musculus

PMID:

28789920

Title:

The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in macrophages

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Biomaterials

Application:

IF:

12.479

Species:

Mus musculus

PMID:

31247479

Title:

Regulation of an osteon-like concentric microgrooved surface on osteogenesis and osteoclastogenesis.

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Cellular & molecular immunology

Application:

IF:

11.53

Species:

Mus musculus

PMID:

31467414

Title:

Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Cellular & molecular immunology

Application:

IF:

11.53

Species:

Mus musculus

PMID:

1467414

Title:

Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection.

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Food & Function

Application:

IF:

5.396

Species:

Mus musculus

PMID:

32270801

Title:

Molecular mechanisms of selenium-biofortified soybean protein and polyphenol conjugates in protecting mouse skin damaged by UV-B

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Frontiers in Pharmacology

Application:

IF:

5.81

Species:

Mus musculus

PMID:

32116720

Title:

Alleviation of Synovial Inflammation of Juanbi-Tang on Collagen-Induced Arthritis and TNF-Tg Mice Model

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Journal of Cellular and Molecular Medicine

Application:

IF:

5.31

Species:

Homo sapiens

PMID:

30821058

Title:

ISG12a and its interaction partner NR4A1 are involved in TRAIL-induced apoptosis in hepatoma cells.

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

J Ethnopharmacol

Application:

IF:

4.36

Species:

Mus musculus

PMID:

32590114

Title:

In vitro and in vivo anti-inflammatory effects of different extracts from Epigynum auritum through down-regulation of NF-κB and MAPK signaling pathways

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Eur J Pharmacol

Application:

IF:

4.432

Species:

Mus musculus

PMID:

33647257

Title:

Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Drug Des Devel Ther

Application:

IF:

4.16

Species:

Homo sapiens

PMID:

33833498

Title:

Chlorogenic Acid Inhibits Human Glioma U373 Cell Progression via Regulating the SRC/MAPKs Signal Pathway: Based on Network Pharmacology Analysis

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Redox Biol

Application:

IF:

11.79

Species:

Mus musculus

PMID:

33865167

Title:

LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

J Ethnopharmacol

Application:

IF:

4.36

Species:

Mus musculus

PMID:

33831464

Title:

In vitro and in vivo relaxation and anti-inflammation of natural flavonoids from Elaeagnus pungens leaf via L-type calcium channel and targeting MAPK signal pathway

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Free Radical Biology and Medicine

Application:

IF:

7.376

Species:

Homo sapiens

PMID:

26456053

Title:

Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Homo sapiens

PMID:

35955862

Title:

ARP2/3 Regulates Fatty Acid Synthesis by Modulating Lipid Droplets Motility - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Canadian respiratory journal

Application:

IF:

2.13

Species:

Rattus norvegicus

PMID:

35958433

Title:

Dexmedetomidine Attenuates LPS-Stimulated Alveolar Type II Cells' Injury through Upregulation of miR-140-3p and Partial Suppression of PD-L1 Involving Inactivating JNK-Bnip3 Pathway - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

PeerJ

Application:

IF:

3.06

Species:

Mus musculus

PMID:

36032961

Title:

Gas chromatography (GC) fingerprinting and immunomodulatory activity of polysaccharide from the rhizome of Menispermum dauricum DC - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Frontiers in nutrition

Application:

IF:

6.59

Species:

Mus musculus

PMID:

35782915

Title:

Structure Characterization, Immunological Activity, and Mechanism of a Polysaccharide From the Rhizome of Menispermum dauricum DC - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Metabolites

Application:

IF:

5.58

Species:

Bos taurus

PMID:

36144207

Title:

Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Journal of agricultural and food chemistry

Application:

IF:

5.89

Species:

Homo sapiens

PMID:

36414003

Title:

Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

International immunopharmacology

Application:

IF:

5.71

Species:

Rattus norvegicus

PMID:

36881980

Title:

Dexmedetomidine attenuates hepatic ischemia-reperfusion injury-induced apoptosis via reducing oxidative stress and endoplasmic reticulum stress

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Metabolites

Application:

IF:

5.58

Species:

Rattus norvegicus

PMID:

36837926

Title:

Expression Silencing of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 Conferred Its Role in Pancreatic β-Cell Physiology and Insulin Secretion - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Veterinary research

Application:

IF:

3.82

Species:

Chlorocebus aethiops

PMID:

36949543

Title:

The novel Nsp9-interacting host factor H2BE promotes PEDV replication by inhibiting endoplasmic reticulum stress-mediated apoptosis - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Journal of controlled release : official journal of the Controlled Release Society

Application:

IF:

11.46

Species:

Homo sapiens

PMID:

37149150

Title:

Delivery of hydroxycamptothecin via sonoporation: An effective therapy for liver fibrosis

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Fish & shellfish immunology

Application:

IF:

4.62

Species:

Ctenopharyngodon idella

PMID:

36842640

Title:

The mitigation mechanism of hesperidin on deoxynivalenol toxicity in grass carp hepatocytes via decreasing ROS accumulation and inhibiting JNK phosphorylation

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Nano-micro letters

Application:

IF:

23.65

Species:

Mus musculus

PMID:

37737506

Title:

Artificial Macrophage with Hierarchical Nanostructure for Biomimetic Reconstruction of Antitumor Immunity - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Journal of nanobiotechnology

Application:

IF:

9.42

Species:

Homo sapiens

PMID:

37789395

Title:

Cerium oxide nanoparticles-carrying human umbilical cord mesenchymal stem cells counteract oxidative damage and facilitate tendon regeneration - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Avian pathology : journal of the W.V.P.A

Application:

IF:

2.72

Species:

Gallus gallus

PMID:

37855868

Title:

STAT5-Mediated Transcription of miR-33-5p in Mycoplasma gallisepticum-Infected DF-1 Cells

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Scientific reports

Application:

IF:

4.99

Species:

Homo sapiens

PMID:

37596361

Title:

Inhibitory effects of Schisandrin C on collagen behavior in pulmonary fibrosis - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Stem Cell Research & Therapy

Application:

IF:

8.079

Species:

Homo sapiens

PMID:

31900224

Title:

Dopamine D1 receptor-mediated activation of the ERK signaling pathway is involved in the osteogenic differentiation of bone mesenchymal stem cells

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Nutrients

Application:

IF:

6.7

Species:

Homo sapiens, Mus musculus

PMID:

36145096

Title:

Polysaccharides from Hericium erinaceus Fruiting Bodies: Structural Characterization, Immunomodulatory Activity and Mechanism - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Homo sapiens, Rattus norvegicus

PMID:

36902422

Title:

Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic -Cell Function - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

BMC complementary medicine and therapies

Application:

IF:

2.83

Species:

Homo sapiens, Mus musculus

PMID:

36474235

Title:

In vitro and in silico analysis of ‘Taikong blue lavender essential oil in LPS-induced HaCaT cells and RAW264.7 murine macrophages - PMC

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Bone

Application:

IF:

4.62

Species:

Homo sapiens, Mus musculus

PMID:

36702335

Title:

Legumain Inhibitor Prevents Breast Cancer Bone Metastasis by Attenuating Osteoclast Differentiation and Function

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Biochemical pharmacology

Application:

IF:

6.1

Species:

Homo sapiens, Mus musculus

PMID:

37558004

Title:

N-3, a novel synthetic derivative of bifendate, inhibits metastasis of triple-negative breast cancer via decreasing p38-regulated FOXC1 protein stability

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Carbohydr Polym .

Application:

IF:

10.723

Species:

Mus musculus

PMID:

33838836

Title:

Value added immunoregulatory polysaccharides of Hericium erinaceus and their effect on the gut microbiota

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

American Journal of Translational Research

Application:

WB, IHC

IF:

3.94

Species:

Mus musculus

PMID:

31105863

Title:

Therapeutic effects of Erbin inhibitor on spinal cord contusion in mice.

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Biomed Pharmacother

Application:

IF:

7.419

Species:

Mus musculus

PMID:

34649337

Title:

Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFB signaling pathway-a study based on network pharmacology

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Cellular & molecular immunology

Application:

WB, IHC

IF:

22.096

Species:

Mus musculus

PMID:

35079145

Title:

DOCK2 regulates antifungal immunity by regulating RAC GTPase activity

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Food & function

Application:

IF:

6.31

Species:

Mus musculus

PMID:

34494061

Title:

The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

J Inflamm Res

Application:

IF:

4.631

Species:

Rattus norvegicus

PMID:

33623411

Title:

Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR- Signaling

References for JNK1 Rabbit pAb (A0288)

Product:

JNK1 Rabbit pAb

Journal:

Mediators of inflammation

Application:

qPCR, WB

IF:

4.52

Species:

Homo sapiens

PMID: