제품 > 항체 > 다중클론항체(pAb)

Myeloperoxidase (MPO) Rabbit pAb (A1374)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Mouse, Rat

Immunofluorescence analysis of rat bone marrow using Myeloperoxidase (MPO) Rabbit pAb (A1374) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of mouse bone marrow using Myeloperoxidase (MPO) Rabbit pAb (A1374) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Overview

Product name	Myeloperoxidase (MPO) Rabbit pAb
Catalog No.	A1374
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 606-745 of human Myeloperoxidase (MPO) (NP_000241.1).
Sequence	CGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREAS
Gene ID
Swiss Prot
Synonyms	MPO; Myeloperoxidase (MPO)
Calculated MW	84kDa
Observed MW	60kDa

Applications

Reactivity	Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	IF/ICC 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Key application	Immunofluorescence
Positive samples
Cellular location	Lysosome.
Customer validation	WB(Cyprinus carpio, Mus musculus, Rattus norvegicus, Homo sapiens) IF(Mus musculus, Gallus gallus, Rattus norvegicus, Homo sapiens) IHC(Mus musculus, Mus musculus ) FC(Saccharomyces cerevisiae) IHC(Rattus norvegicus) IF(Rattus norvegicus) Other(Homo sapiens)

Documents

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Lot number

Research Area

제품재조합 단백질Drug Targets

Myeloperoxidase (MPO) Rabbit pAb images

Immunofluorescence - Myeloperoxidase (MPO) Rabbit pAb (A1374)

* For research use only. Not for therapeutic or diagnostic purposes.

Product Protocols

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Journal of Hazardous Materials

Application:

IF:

12.2

Species:

Cyprinus carpio

PMID:

31879111

Title:

Avermectin inhibits neutrophil extracellular traps release by activating PTEN demethylation to negatively regulate the PI3K-ERK pathway and reducing respiratory burst in carp

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Drug Des Devel Ther

Application:

IF:

4.7

Species:

Mus musculus

PMID:

34321869

Title:

Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Chin Med

Application:

IF:

5.3

Species:

Mus musculus

PMID:

34399822

Title:

Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Antioxidants (Basel)

Application:

IF:

7.7

Species:

Mus musculus

PMID:

33445746

Title:

Lipocalin-2 Deficiency Reduces Oxidative Stress and Neuroinflammation and Results in Attenuation of Kainic Acid-Induced Hippocampal Cell Death

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

PLoS Negl Trop Dis

Application:

IHC

IF:

3.4

Species:

Mus musculus

PMID:

34161342

Title:

Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Front Pharmacol

Application:

IHC

IF:

5.6

Species:

Mus musculus

PMID:

34803718

Title:

JieZe-1 Alleviates HSV-2 Infection-Induced Genital Herpes in Balb/c Mice by Inhibiting Cell Apoptosis via Inducing Autophagy

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Shock

Application:

IF:

2.7

Species:

Rattus norvegicus

PMID:

33927140

Title:

Vagus Nerve Stimulation Protects Enterocyte Glycocalyx After Hemorrhagic Shock Via the Cholinergic Anti-Inflammatory Pathway

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

American journal of translational research

Application:

IF:

1.7

Species:

Mus musculus

PMID:

35702070

Title:

SIRT1 ameliorates renal ischemia-reperfusion injury through suppressing endoplasmic reticulum stress-mediated autophagy - PMC

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Annals of translational medicine

Application:

IF:

Species:

Mus musculus

PMID:

35845498

Title:

Midkine promotes kidney injury in diabetic kidney disease by increasing neutrophil extracellular traps formation - PMC

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

6.9

Species:

Rattus norvegicus

PMID:

36076491

Title:

Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Journal of investigative surgery : the official journal of the Academy of Surgical Research

Application:

IF:

2.1

Species:

Mus musculus

PMID:

36603844

Title:

Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Toxicology letters

Application:

IF:

2.9

Species:

Mus musculus

PMID:

36460194

Title:

Hepatocytic AP-1 and STAT3 contribute to chemotaxis in alphanaphthylisothiocyanate-induced cholestatic liver injury

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

International immunopharmacology

Application:

IF:

4.8

Species:

Homo sapiens

PMID:

36417823

Title:

Targeted inhibition of FcRn reduces NET formation to ameliorate experimental ulcerative colitis by accelerating ANCA clearance

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Experimental neurology

Application:

IF:

4.6

Species:

Homo sapiens

PMID:

36914085

Title:

Exercise pretreatment alleviates neuroinflammation and oxidative stress by TFEB-mediated autophagic flux in mice with ischemic stroke

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Environmental pollution (Barking, Essex : 1987)

Application:

IF:

7.6

Species:

Gallus gallus

PMID:

37209896

Title:

Fluoride induces neutrophil extracellular traps and aggravates brain inflammation by disrupting neutrophil calcium homeostasis and causing ferroptosis

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

International journal of biological macromolecules

Application:

IF:

7.7

Species:

Mus musculus

PMID:

37330081

Title:

Ganoderma lucidum polysaccharide peptides GL-PPSQ2 alleviate intestinal ischemia-reperfusion injury via inhibiting cytotoxic neutrophil extracellular traps

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Environmental Research

Application:

IF:

8.3

Species:

Mus musculus

PMID:

37271434

Title:

Black carbon nanoparticles activate the crosstalk mechanism between necroptosis and macrophage extracellular traps to change macrophages fate

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Frontiers in pharmacology

Application:

IF:

5.6

Species:

Rattus norvegicus

PMID:

36865920

Title:

The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats - PMC

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Journal of Immunological Methods

Application:

IF:

2.2

Species:

Saccharomyces cerevisiae

PMID:

38432292

Title:

High-resolution epitope mapping of commercial antibodies to ANCA antigens by yeast surface display

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Journal of photochemistry and photobiology. B, Biology

Application:

IHC

IF:

3.9

Species:

Mus musculus

PMID:

38387147

Title:

Biphasic photobiomodulation of inflammation in mouse models of common wounds, infected wounds, and diabetic wounds

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Pancreatology

Application:

WB, IHC, IF

IF:

2.8

Species:

Rattus norvegicus

PMID:

34810073

Title:

Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight

References for Myeloperoxidase (MPO) Rabbit pAb (A1374)

Product:

Myeloperoxidase (MPO) Rabbit pAb

Journal:

Respiratory research

Application:

IF:

5.8

Species:

Rattus norvegicus

PMID:

35906634