제품 > 항체 > 다중클론항체(pAb)

OCT4 Rabbit pAb (A7920)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse

Western blot analysis of lysates from Mouse embryo, using OCT4 Rabbit pAb (A7920) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 20s.

ABclonal:Immunohistochemistry - OCT4 Rabbit pAb (A7920)

Immunohistochemistry analysis of paraffin-embedded Mouse fetal Brain using OCT4 Rabbit pAb (A7920) at dilution of 1:50 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Review

Overview

Product name	OCT4 Rabbit pAb
Catalog No.	A7920
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 210-310 of human 4-oct (NP_002692.2).
Sequence	EADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPV
Gene ID
Swiss Prot
Synonyms	OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; Oct3/4
Calculated MW	39kDa
Observed MW	45kDa

Applications

Reactivity	Human, Mouse
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 IHC-P 1:50 - 1:200
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry
Positive samples	Mouse embryo
Cellular location	Cytoplasm, Nucleus.
Customer validation	(HeLa cells) WB(Homo sapiens, Mus musculus) IHC(Mus musculus, Homo sapiens)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

Research Area

OCT4 Rabbit pAb images

Western blot - OCT4 Rabbit pAb (A7920)

Immunohistochemistry - OCT4 Rabbit pAb (A7920)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A7920

Please submit reviews to your technical sales specialist directly. Alternatively, email us at info@abclonal.co.kr

Reviews List

Product Protocols

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Cell death & disease

Application:

IF:

8.1

Species:

Homo sapiens

PMID:

30631035

Title:

Acidosis enhances the self-renewal and mitochondrial respiration of stem cell-like glioma cells through CYP24A1-mediated reduction of vitamin D.

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

International journal of developmental neuroscience

Application:

IHC

IF:

1.8

Species:

Mus musculus

PMID:

31059735

Title:

Musashi-2 and related stem cell proteins in the mouse suprachiasmatic nucleus and their potential role in circadian rhythms.

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Cellular oncology (Dordrecht)

Application:

IF:

4.9

Species:

Homo sapiens

PMID:

31292920

Title:

QKI deficiency maintains glioma stem cell stemness by activating the SHH/GLI1 signaling pathway

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Stem Cells International

Application:

IF:

3.8

Species:

Mus musculus

PMID:

31781236

Title:

MicroRNA-150 Modulates Adipogenic Differentiation of Adipose-Derived Stem Cells by Targeting Notch3

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of Cellular Physiology

Application:

IHC

IF:

5.6

Species:

Homo sapiens

PMID:

27891591

Title:

NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Oncology Reports

Application:

IHC

IF:

3.8

Species:

Homo sapiens

PMID:

31894290

Title:

Lung adenocarcinoma resistance to therapy with EGFR‑tyrosine kinase inhibitors is related to increased expression of cancer stem cell markers SOX2, OCT4 and NANOG

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of Cancer

Application:

IF:

3.3

Species:

Homo sapiens

PMID:

32231716

Title:

Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Aging

Application:

IF:

3.9

Species:

Homo sapiens

PMID:

32003751

Title:

The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Cell Reports

Application:

IF:

7.5

Species:

Mus musculus

PMID:

31914400

Title:

DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Pharmaceutics

Application:

IF:

5.4

Species:

Homo sapiens

PMID:

35214008

Title:

CHRNA5 Contributes to Hepatocellular Carcinoma Progression by Regulating YAP Activity

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

International journal of molecular sciences

Application:

IF:

5.6

Species:

Mus musculus

PMID:

36293000

Title:

Engineered Immature Testicular Tissue by Electrospun Mats for Prepubertal Fertility Preservation in a Bioluminescence Imaging Transgenic Mouse Model - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

International journal of molecular sciences

Application:

IHC

IF:

5.6

Species:

Mus musculus

PMID:

35955560

Title:

Tracking Immature Testicular Tissue after Vitrification In Vitro and In Vivo for Pre-Pubertal Fertility Preservation: A Translational Transgenic Mouse Model - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Frontiers in cell and developmental biology

Application:

IF:

4.6

Species:

Homo sapiens

PMID:

35769259

Title:

Telomere Attrition in Induced Pluripotent Stem Cell-Derived Neurons From ALS/FTD-Related C9ORF72 Repeat Expansion Carriers - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Medical oncology (Northwood, London, England)

Application:

IF:

2.8

Species:

Homo sapiens

PMID:

36625999

Title:

SRC-3/TRAF4 facilitates ovarian cancer development by activating the PI3K/AKT signaling pathway - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of translational medicine

Application:

IF:

8.4

Species:

Homo sapiens

PMID:

37149661

Title:

MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of cancer research and clinical oncology

Application:

IF:

2.7

Species:

Homo sapiens

PMID:

37668799

Title:

Integrated bioinformatics and validation reveal SOX12 as potential biomarker in colon adenocarcinoma based on an immune infiltration-related ceRNA network

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of cellular and molecular medicine

Application:

IF:

5.3

Species:

Mus musculus

PMID:

37614114

Title:

Bazi Bushen alleviates skin senescence by orchestrating skin homeostasis in SAMP6 mice

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Aging

Application:

IF:

3.9

Species:

Homo sapiens

PMID:

37433225

Title:

Galectin-1-mediated MET/AXL signaling enhances sorafenib resistance in hepatocellular carcinoma by escaping ferroptosis - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

BMC cancer

Application:

IF:

3.8

Species:

Homo sapiens

PMID:

35761259

Title:

PIK3R3, a regulatory subunit of PI3K, modulates ovarian cancer stem cells and ovarian cancer development and progression by integrative analysis - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Oncogene

Application:

IF:

6.9

Species:

Homo sapiens

PMID:

28394339

Title:

NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

6.9

Species:

Homo sapiens

PMID:

36271541

Title:

Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Phytomedicine : international journal of phytotherapy and phytopharmacology

Application:

IF:

6.7

Species:

Homo sapiens

PMID:

38350242

Title:

Ginsenoside Rg3 suppresses vasculogenic mimicry by impairing DVL3-maintained stemness via PAAD cell-derived exosomal miR-204 in pancreatic

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Molecular biotechnology

Application:

IF:

2.4

Species:

Homo sapiens

PMID:

38573544

Title:

EHMT2 Suppresses ARRB1 Transcription and Activates the Hedgehog Signaling to Promote Malignant Phenotype and Stem Cell Property in Oral Squamous Cell

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Advanced healthcare materials

Application:

IF:

Species:

Mus musculus

PMID:

36782053

Title:

Hierarchically injectable hydrogel sequentially delivers antagomiR467a3ploaded and antagomiR8745ploaded satellitecelltargeting bioengineered

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Cell death discovery

Application:

IF:

7.1

Species:

Homo sapiens

PMID:

38851743

Title:

Sponging of five tumour suppressor miRNAs by lncRNA-KCNQ1OT1 activates BMPR1A/BMPR1B-ACVR2A/ACVR2B signalling and promotes chemoresistance to

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Biology direct

Application:

IF:

7.2

Species:

Mus musculus

PMID:

39294751

Title:

ZFP64 drives glycolysis-mediated stem cell-like properties and tumorigenesis in breast cancer - PMC

References for OCT4 Rabbit pAb (A7920)

Product:

OCT4 Rabbit pAb

Journal:

Journal of cellular and molecular medicine

Application:

IF:

5.3

Species:

Mus musculus

PMID:

39469911

Title:

Bazi Bushen attenuates osteoporosis in SAMP6 mice by regulating PI3KAKT and apoptosis pathways - PMC

Publishing research using A7920? Please let us know so that we can cite the reference in this datasheet.

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제품 > 항체 > 다중클론항체(pAb)

OCT4 Rabbit pAb (A7920)

Overview

Background

Immunogen information

Applications

Documents

Certificate of Compliance

Research Area

OCT4 Rabbit pAb images

Submit an review for A7920

Reviews List

Product Protocols

항체 (1)

Secondary Antibodies (26)