| Product name | Rabbit anti-Human IFN-α mAb (DET) |
|---|---|
| Catalog No. | RM17742 |
| Catagory | Elisa Antibody Kit |
| Application | ELISA, Multiplex, CLIA |
| Description | This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24-188 of human IFN-α (NP_000596.2). |
| Purirty | Affinity purification |
| Ig Type | Rabbit IgG |
| Formulation | Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4. |
| CrossReactivity | No cross-reactivity in ELISA with recombinant hIFN-β、hIFN-Lambda 1、hIFN-Lambda 2、hIFN-γ、mIFN-γ、mIFN-β、rIFN-γ |
| Storage | Store at -20℃. Avoid repeated freeze-thaw cycles. |
Human IFN-α Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| ELISA | Capture | 1-4ug/mL | Rabbit anti-Human IFN-α mAb(Cat. No.RM17741) |
| Detection | 0.05-0.2ug/mL | Rabbit anti-Human IFN-α mAb(Cat. No.RM17742） | |
| Standard | 1.56-100pg/mL | Rabbit anti-Human IFN-α Protein | |
| ELISA | Capture | 1-4ug/mL | Rabbit anti-Human IFN-α mAb(Cat. No.RM17817) |
| Detection | 0.05-0.2ug/mL | Rabbit anti-Human IFN-α mAb(Cat. No.RM17742) | |
| Standard | 1.56-100pg/mL | Recombinant Human IFN-α Protein |
