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Rabbit anti-Human sST2 mAb (RM17779)

Datasheet

ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)

Overview

Product nameRabbit anti-Human sST2 mAb
Catalog No.RM17779
CatagoryElisa Antibody Kit
ApplicationELISA
DescriptionReceptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization
ImmunogenRecombinant Human sST2 Protein
PurirtyAffinity purification
Ig TypeRabbit IgG
FormulationSupplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivityNo significant cross-reactivity or interference between sST2 and analogues was observed.
StorageStore at -20℃.

Avoid repeated freeze-thaw cycles.

Application

Human sST2 Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture1-4ug/mLRabbit anti-Human sST2 mAb(Cat. No.RM17778)
Detection0.015-0.06ug/mLRabbit anti-Human sST2 mAb(Cat. No.RM17779)
Standard7.8-500pg/mLRecombinant Human sST2 Protein
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)}

- Rabbit anti-Human sST2 mAb (RM17779)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)}

- Rabbit anti-Human sST2 mAb (RM17779)

Fromthe comparison of the standard curve, it is found that ABclonal has highsensitivity.
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)}

- Rabbit anti-Human sST2 mAb (RM17779)

No significant cross-reactivity or interference was observed.
ABclonal: - Rabbit anti-Human sST2 mAb (RM17779)}

- Rabbit anti-Human sST2 mAb (RM17779)

Placed at 37°C for 3 days, the stability of the standard curve all conformto CV <10%.
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