제품 > 항체 > 다중클론항체(pAb)

SLC5A1 Rabbit pAb (A11976)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human

Western blot analysis of lysates from 293F cells, using SLC5A1 Rabbit pAb (A11976) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45s.

Overview

Product name	SLC5A1 Rabbit pAb
Catalog No.	A11976
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 400-500 of human SLC5A1 (NP_000334.1).
Sequence	SASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLTKPIPDVHLYRLCWSLRNSKEERIDLDAEEENIQEGPKETIEIETQVPEKKKGIFRRAYDLFCGLEQHGAPKMTEEEEKAMKMKMTDTSEKPLWRTVLNVNGIILVTVAVFCHAYFA
Gene ID
Swiss Prot
Synonyms	NAGT; SGLT1; SGLT-1; D22S675; SLC5A1
Calculated MW	73kDa
Observed MW	74kDa

Applications

Reactivity	Human
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting
Positive samples	293F
Cellular location	Membrane, Multi-pass membrane protein.
Customer validation	WB(Sus scrofa, Rattus norvegicus, Mus musculus) IHC(Gallus gallus)

Documents

Certificate of Compliance

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Lot number

Research Area

연구내분비 & 대사탄수화물 대사

SLC5A1 Rabbit pAb images

Western blot - SLC5A1 Rabbit pAb (A11976)

* For research use only. Not for therapeutic or diagnostic purposes.

Product Protocols

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Journal of Agricultural and Food Chemistry

Application:

IF:

5.7

Species:

Sus scrofa

PMID:

32252520

Title:

An Early Fecal Microbiota Transfer Improves the Intestinal Conditions on Microflora and Immunoglobulin and Antimicrobial Peptides in Piglets

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Microb Pathog

Application:

IHC

IF:

3.3

Species:

Gallus gallus

PMID:

33383151

Title:

Sex differences in growth performance are related to cecal microbiota in chicken

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Mol Cell Biochem

Application:

IF:

3.5

Species:

Rattus norvegicus

PMID:

33608832

Title:

Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium-glucose cotransporter 1

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Nutrients

Application:

IF:

5.9

Species:

Mus musculus

PMID:

34065342

Title:

Acute Low-Intensity Treadmill Running Upregulates the Expression of Intestinal Glucose Transporters via GLP-2 in Mice

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Arch Biochem Biophys

Application:

IF:

3.8

Species:

Mus musculus

PMID:

34153296

Title:

Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Mol Cell Biol

Application:

IF:

3.2

Species:

Mus musculus

PMID:

34842443

Title:

Inhibition of SGLT1 alleviates the glycemic variability-induced cardiac fibrosisvia inhibiting activations of macrophage and cardiac fibroblast

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Biochemistry and cell biology = Biochimie et biologie cellulaire

Application:

IF:

2.4

Species:

Rattus norvegicus

PMID:

33259229

Title:

Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

International immunopharmacology

Application:

IF:

4.8

Species:

Mus musculus

PMID:

35841866

Title:

SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

The British journal of nutrition

Application:

IF:

Species:

Rattus norvegicus

PMID:

36329653

Title:

Female athlete triad affects rat intestinal morphology and sucrase-isomaltase expression

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Poultry science

Application:

IF:

4.4

Species:

Mus musculus

PMID:

37716231

Title:

Selenoprotein K knockdown induces apoptosis in skeletal muscle satellite cells via calcium dyshomeostasis-mediated endoplasmic reticulum stress - PMC

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

International journal of molecular sciences

Application:

IF:

5.6

Species:

Rattus norvegicus

PMID:

38003644

Title:

Ageing-Related Alterations in Renal Epithelial Glucose Transport - PMC

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Acta biochimica et biophysica Sinica

Application:

IF:

3.3

Species:

Mus musculus

PMID:

37587757

Title:

Hydrogen sulfide ameliorates senescence in vascular endothelial cells through ameliorating inflammation and activating PPAR/SGLT2/STAT3 signaling pathway - PMC

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Cell reports. Medicine

Application:

IF:

11.7

Species:

Mus musculus

PMID:

38118414

Title:

Dapagliflozin protects against chronic heart failure in mice by inhibiting macrophage-mediated inflammation, independent of SGLT2 - PMC

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

International journal of pharmaceutics

Application:

IF:

5.3

Species:

Mus musculus,Rattus norvegicus

PMID:

37254285

Title:

Strain Differences in the Drug Transport Capacity of Intestinal Glucose Transporters in SpragueDawley versus Wistar Rats, C57BL/6J versus Kunming Mice

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Application:

IF:

Species:

Mus musculus

PMID:

38868175

Title:

Effects of novel beta-lactam, MC-100093, and ceftriaxone on astrocytic glutamate transporters and neuroinflammatory factors in nucleus accumbens of C57BL/6 mice exposed to escalated doses of morphine - PMC

References for SLC5A1 Rabbit pAb (A11976)

Product:

SLC5A1 Rabbit pAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

6.9

Species:

Rattus norvegicus

PMID:

38574614