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TIRAP Rabbit pAb (A1943)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human

ABclonal:Immunohistochemistry - TIRAP Rabbit pAb (A1943)

Immunohistochemistry analysis of paraffin-embedded human liver cancer using TIRAP Rabbit pAb (A1943) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

ABclonal:Immunohistochemistry - TIRAP Rabbit pAb (A1943)

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using TIRAP Rabbit pAb (A1943) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Overview

Product nameTIRAP Rabbit pAb
Catalog No.A1943
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP (NP_001034750.1).
SequenceMASSTSLPAPGSRPKKPLGKMADWFRQTLLKKPKKRPNSPESTSSDASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYDVCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCRVLLITPGFLQDPWCKYQMLQALTEAPGAEGCTIPLLSGLSRAAYPPELRFMYYVDGRGPDGGFRQVKEAVMRYLQTLS
Gene ID
Swiss Prot
SynonymsMal; wyatt; BACTS1; MyD88-2; TIRAP
Calculated MW24kDa
Observed MW
ReactivityHuman
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    
Positive samples
Cellular locationCell membrane, Cytoplasm, Membrane

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ABclonal:Immunohistochemistry - TIRAP Rabbit pAb (A1943)}

Immunohistochemistry - TIRAP Rabbit pAb (A1943)

Immunohistochemistry analysis of paraffin-embedded human liver cancer using TIRAP Rabbit pAb (A1943) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
ABclonal:Immunohistochemistry - TIRAP Rabbit pAb (A1943)}

Immunohistochemistry - TIRAP Rabbit pAb (A1943)

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using TIRAP Rabbit pAb (A1943) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (2)

Secondary Antibodies (26)