제품 > 항체 > 다중클론항체(pAb)

c-Myc Rabbit pAb (A1309)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse

Western blot analysis of lysates from HeLa cells, using c-Myc Rabbit pAb (A1309) at 1:400 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.

Review

Overview

Product name	c-Myc Rabbit pAb
Catalog No.	A1309
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 347-439 of human c-Myc (NP_001341799.1).
Sequence	LRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRRE
Gene ID
Swiss Prot
Synonyms	MRTL; MYCC; c-Myc; bHLHe39
Calculated MW	51kDa
Observed MW	60kDa

Applications

Reactivity	Human, Mouse
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting
Positive samples	HeLa
Cellular location	Nucleus, nucleolus, nucleoplasm.
Customer validation	(unknow, Human Bladder Cancer) WB(Homo sapiens, Mus musculus, Sus scrofa, Mus musculus, Gallus gallus, Oryctolagus cuniculus, Other) IHC(Homo sapiens) IP(Homo sapiens, Mus musculus) ChIP(Homo sapiens, Mus musculus) Co-IP(Homo sapiens, Mus musculus) IF(Danio rerio) RT-qPCR(Danio rerio) Co-IP(Homo sapiens, Gallus gallus) ChIP(Homo sapiens, Mus musculus)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

Research Area

c-Myc Rabbit pAb images

Western blot - c-Myc Rabbit pAb (A1309)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A1309

Please submit reviews to your technical sales specialist directly. Alternatively, email us at info@abclonal.co.kr

Reviews List

Product Protocols

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

tumor biology

Application:

IF:

Species:

Homo sapiens

PMID:

28671049

Title:

Clinicopathological significance of c-MYC in esophageal squamous cell carcinoma

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Journal of cellular and molecular medicine

Application:

IF:

5.3

Species:

Homo sapiens

PMID:

30407707

Title:

MiR-520b promotes the progression of non-small cell lung cancer through activating Hedgehog pathway.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Oncogenesis

Application:

IF:

5.9

Species:

Mus musculus

PMID:

30573731

Title:

CD36 plays a critical role in proliferation, migration and tamoxifen-inhibited growth of ER-positive breast cancer cells.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Oxidative medicine and cellular longevity

Application:

IF:

Species:

Mus musculus

PMID:

31531187

Title:

Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

American Journal of Physiology. Gastrointestinal and Liver Physiology

Application:

IF:

3.9

Species:

Homo sapiens

PMID:

31604033

Title:

Hepatitis B virus-triggered PTEN/β-catenin/c-Myc signaling enhances PD-L1 expression to promote immune evasion

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

International Journal of Molecular Sciences

Application:

IF:

5.6

Species:

Mus musculus

PMID:

28749413

Title:

PGK1 Drives Hepatocellular Carcinoma Metastasis by Enhancing Metabolic Process.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cell Cycle

Application:

IF:

3.4

Species:

Sus scrofa

PMID:

29119857

Title:

miR-638 Inhibits immature Sertoli cell growth by indirectly inactivating PI3K/AKT pathway via SPAG1 gene.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Protein Cell

Application:

IF:

13.6

Species:

Homo sapiens

PMID:

32748349

Title:

KIF2C: a novel link between Wnt/尾-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Reprod Domest Anim

Application:

IF:

1.6

Species:

Sus scrofa

PMID:

33305371

Title:

AR regulates porcine immature Sertoli cell growth via binding to RNF4 and miR‐124a

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Adv Sci (Weinh)

Application:

IF:

15.1

Species:

Mus musculus

PMID:

34026434

Title:

PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Neoplasia

Application:

IF:

6.3

Species:

Homo sapiens

PMID:

34325342

Title:

PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

3 Biotech

Application:

IF:

2.6

Species:

Homo sapiens

PMID:

34458056

Title:

Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

ACS applied bio materials

Application:

IF:

4.6

Species:

Homo sapiens

PMID:

35005910

Title:

A Lipidated Peptide with Mitochondrial Membrane Localization in Human A549 Lung Cells: From Enhanced Cell-Penetrating Properties to Biological Activity Mechanism

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Materials today. Bio

Application:

IF:

8.7

Species:

Homo sapiens

PMID:

36199559

Title:

Attachment of -tBu groups to aza-BODIPY core at 3,5-sites with ultra-large Stokes shift to enhance photothermal therapy through apoptosis mechanism - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cancers

Application:

IF:

5.2

Species:

Homo sapiens

PMID:

36497264

Title:

Canonical WNT Signaling Activated by WNT7B Contributes to L-HBs-Mediated Sorafenib Resistance in Hepatocellular Carcinoma by Inhibiting Mitophagy - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Environmental toxicology

Application:

IF:

4.5

Species:

Homo sapiens

PMID:

37186152

Title:

KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial‐mesenchymal transition and stemness through Wnt/β‐catenin signaling

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Food & function

Application:

IF:

5.1

Species:

Mus musculus

PMID:

37183435

Title:

Myosin heavy chain-derived peptide of Gadus morhua promotes proliferation and differentiation in osteoblasts and bone formation and maintains bone homeostasis in …

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cancer cell international

Application:

IF:

6.4

Species:

Homo sapiens

PMID:

37848941

Title:

KHDRBS3 accelerates glycolysis and promotes malignancy of hepatocellular carcinoma via upregulating 14-3-3ζ - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

6.9

Species:

Mus musculus

PMID:

37722192

Title:

Phenylethanoid glycosides derived from Cistanche deserticola promote neurological functions and the proliferation of neural stem cells for improving ischemic

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Experimental and therapeutic medicine

Application:

IF:

2.4

Species:

Homo sapiens

PMID:

37954123

Title:

miR-149-3p suppresses the proliferation and metastasis of glioma cells by targeting the CBX2/Wnt/-catenin pathway - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cancer gene therapy

Application:

IF:

4.8

Species:

Mus musculus

PMID:

37037907

Title:

PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

PeerJ

Application:

IHC

IF:

2.3

Species:

Homo sapiens

PMID:

37609434

Title:

Identification of hub genes associated with oxidative stress in heart failure and their correlation with immune infiltration using bioinformatics analysis - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Aging (Albany NY)

Application:

IF:

3.9

Species:

Homo sapiens

PMID:

33099540

Title:

CUEDC1 inhibits epithelial-mesenchymal transition via the TRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Nature communications

Application:

IF:

16.6

Species:

Homo sapiens, Mus musculus

PMID:

31484922

Title:

CD36 inhibits -catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cell Rep

Application:

WB, IP

IF:

7.5

Species:

Homo sapiens, Mus musculus

PMID:

34758320

Title:

Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Stem cell research & therapy

Application:

IF:

8.1

Species:

Homo sapiens

PMID:

35851415

Title:

Extracellular matrix derived from Whartons Jelly-derived mesenchymal stem cells promotes angiogenesis via integrin V3/c-Myc/P300/VEGF - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Journal of cellular and molecular medicine

Application:

IF:

5.3

Species:

Homo sapiens

PMID:

37859585

Title:

Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Environmental toxicology

Application:

IF:

4.5

Species:

Homo sapiens

PMID:

38317508

Title:

LINC01572 promotes triplenegative breast cancer progression through EIF4A3mediated catenin mRNA nuclear exportation

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cancer letters

Application:

IF:

9.1

Species:

Homo sapiens

PMID:

38331088

Title:

Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Heliyon

Application:

IF:

Species:

Homo sapiens

PMID:

38163179

Title:

Therapeutic potential of anti-PIK3CG treatment for multiple myeloma via inhibiting c-Myc pathway - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Nature communications

Application:

IF:

16.6

Species:

Mus musculus

PMID:

38424044

Title:

MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Hepatology (Baltimore, Md.)

Application:

ChIP, Co-IP

IF:

12.9

Species:

Homo sapiens, Mus musculus

PMID:

30180281

Title:

Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR1923pXIAP via NFB Signaling

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

J Agric Food Chem

Application:

IF:

5.7

Species:

Mus musculus

PMID:

34928143

Title:

Characterizations and the Mechanism Underlying Osteogenic Activity of Peptides from Enzymatic Hydrolysates of Stichopus japonicus

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Journal of cardiovascular development and disease

Application:

IF, RT-qPCR

IF:

4.4

Species:

Danio rerio

PMID:

37367411

Title:

Tg(Δ113p53:cmyc) Transgene Upregulates glut1 Expression to Promote Zebrafish Heart Regeneration - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Application:

WB, Co-IP

IF:

4.6

Species:

Homo sapiens, Gallus gallus

PMID:

29670864

Title:

Mechanism of Apoptosis Induction by Mycoplasmal Nuclease MGA_0676 in Chicken Embryo Fibroblasts

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cells

Application:

IF:

7.7

Species:

Mus musculus

PMID:

34685756

Title:

The Involvement of Macrophage Colony Stimulating Factor on Protein Hydrolysate Injection Mediated Hematopoietic Function Improvement

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cancer research

Application:

WB, ChIP

IF:

12.5

Species:

Homo sapiens, Mus musculus

PMID:

34535458

Title:

Megakaryocytes mediate hyperglycemia-induced tumor metastasis

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Nature communications

Application:

IF:

16.6

Species:

Mus musculus

PMID:

31484922

Title:

CD36 inhibits -catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cell death & disease

Application:

IF:

8.1

Species:

Homo sapiens, Mus musculus

PMID:

35985991

Title:

Lenvatinib for effectively treating antiangiogenic drug-resistant nasopharyngeal carcinoma - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cell communication and signaling : CCS

Application:

IF:

7.5

Species:

Homo sapiens

PMID:

37596667

Title:

NEK8 regulates colorectal cancer progression via phosphorylating MYC - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Nature communications

Application:

IF:

16.6

Species:

Mus musculus

PMID:

38504107

Title:

Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

iScience

Application:

IF:

5.8

Species:

Homo sapiens

PMID:

37035004

Title:

FSBP suppresses tumor cell migration by inhibiting the JNK pathway - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cell chemical biology

Application:

IF:

8.6

Species:

Homo sapiens,Mus musculus

PMID:

37751743

Title:

Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

EBioMedicine

Application:

IF:

9.7

Species:

Homo sapiens

PMID:

38954976

Title:

Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Nature communications

Application:

IF:

16.6

Species:

Oryctolagus cuniculus

PMID:

39117705

Title:

Blocker-SELEX: a structure-guided strategy for developing inhibitory aptamers disrupting undruggable transcription factor interactions - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Journal of virology

Application:

IF:

Species:

Other

PMID:

37162335

Title:

The Host Protein CAD Regulates the Replication of FMDV through the Function of Pyrimidines De Novo Synthesis - PMC

References for c-Myc Rabbit pAb (A1309)

Product:

c-Myc Rabbit pAb

Journal:

Cells

Application:

IF:

5.1

Species:

Homo sapiens

PMID:

39513905

Title:

Ubiquitin-Specific Protease 1 Promotes Bladder Cancer Progression by Stabilizing c-MYC - PMC

Publishing research using A1309? Please let us know so that we can cite the reference in this datasheet.

항체 (9)

Secondary Antibodies (25)

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제품 > 항체 > 다중클론항체(pAb)

c-Myc Rabbit pAb (A1309)

Overview

Background

Immunogen information

Applications

Documents

Certificate of Compliance

Research Area

c-Myc Rabbit pAb images

Submit an review for A1309

Reviews List

Product Protocols

항체 (9)

Secondary Antibodies (25)