Biotinylated Recombinant Human IL-17A/CTLA-8 Protein (RP02410B)

Overview

Product name	Biotinylated Recombinant Human IL-17A/CTLA-8 Protein
Catalog No.	RP02410B
Description	Biotinylated Recombinant Human IL-17A/CTLA-8 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Gly24-Ala155) of Human IL-17A fused with a His and Avi tag at the C-terminal.
Purity	> 95% by Tris-Bis PAGE
Endotoxin	< 1 EU/μg of the protein by LAL method.
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Species	Human
Calculated MW	18.2 kDa

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

Product information

Synonym	IL17A; CTLA-8; CTLA8; IL-17; IL-17A; IL17; interleukin-17A; CTLA-8; CTLA8; IL-17; IL-17A; IL17
Expression Host	HEK293 cells
Tag	C-His&Avi
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.