Overview
| Product name | Recombinant Cynomolgus Guanylyl cyclase C/GUCY2C Protein |
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| Catalog No. | RP02645 |
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| Description | Recombinant Cynomolgus Guanylyl cyclase C/GUCY2C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser24-Gln430) of cynomolgus Guanylyl cyclase C/GUCY2C (Accession #XP_005570270.1) fused with His tag at the C-terminus. |
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| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
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| Endotoxin | Less than 1EU per μg by the LAL method. |
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| Species | Cynomolgus |
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| Calculated MW | 47.2 kDa |
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Background
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatichanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Product information
| Synonym | Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
