Overview
| Product name | Recombinant Cynomolgus IL-23A&Mouse IL-12B Protein |
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| Catalog No. | RP02725 |
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| Description | Recombinant Cynomolgus IL-23A&Mouse IL-12B Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val22-Pro189(Cynomolgus IL-23A)&Met23-Ser335(Mouse IL-12B)) of cynomolgus IL-23A&mouse IL-12B (Accession #A0A2K5TLV4-1(Cynomolgus IL-23A)&P43432-1(Mouse IL-12B)) fused with His tag at the N-terminus. |
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| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
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| Endotoxin | Less than 1EU per μg by the LAL method. |
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| Species | Cynomolgus&Mouse |
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| Calculated MW | 19.5 kDa(Cynomolgus IL-23 alpha), 35.8 kDa(Mouse IL-12 beta) |
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Background
Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common β subunit p40 and the specific cytokine α subunit p35 and p19, respectively. IL-12 signals via the IL-12Rβ1·IL-12Rβ2 receptor complex, and IL-23 uses also IL-12Rβ1 but engages IL-23R as second receptor.
Product information
| Synonym | IL23 alpha; IL12 beta; IL23 alpha&IL12 beta |
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| Expression Host | HEK293 cells |
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| Tag | N-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
