Overview
| Product name | Recombinant Cynomolgus NKG2A&KLRD1/CD159a&CD94 Protein |
|---|
| Catalog No. | RP02713 |
|---|
| Description | Recombinant Cynomolgus NKG2A&KLRD1/CD159a&CD94 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Pro94-Leu233)&(Lys32-Ile179) of Cynomolgus NKG2A&KLRD1/CD159a&CD94 (Accession #) fused with His tag and Flag tag at the C-terminal. |
|---|
| Purity | > 95% as determined by Tris-Bis PAGE |
|---|
| Endotoxin | Less than 1EU per μg by the LAL method. |
|---|
| Species | Cynomolgus |
|---|
| Calculated MW | 17.01 kDa(NkG2A), 18.27 kDa(CD94) |
|---|
Background
The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies.
Product information
| Synonym | CD159a; NKG2A; NKG2-A; CD94; NKG2A&CD94 |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His&Flag |
|---|
| Swiss-Prot | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
