Recombinant Human Annexin A6/ANXA6 Protein (RP02985)

Overview

Product name	Recombinant Human Annexin A6/ANXA6 Protein
Catalog No.	RP02985
Description	Recombinant Human Annexin A6/ANXA6 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala2-Asp673) of Human Annexin A6/ANXA6 (Accession #NP_001146.2) fused with a 6×His tag at the C-terminus.
Purity	> 95% by SDS-PAGE.
Endotoxin	<1EU/μg
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Species	Human
Calculated MW	76.9 kDa

Annexin A6 (ANAX6) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A6 is a secreted protein and locates on the cell surface. Annexin A6 contains 8 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA6 is involved in the regulation of the release of Ca2+ from intracellular stores and may be associated with CD21. In addition, ANXA6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Product information

Synonym	Annexin A6; 67 kDa Calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; ANXA6; ANX6
Expression Host	E. coli
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.