Overview
| Product name | Recombinant Human Biglycan/BGN Protein |
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| Catalog No. | RP00141 |
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| Description | Recombinant Human Biglycan/BGN Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp38-Lys368) of human Biglycan/BGN (Accession #NP_001702.1) fused with a 6×His tag at the C-terminus. |
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| Purity | > 80% by SDS-PAGE. |
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| Endotoxin | < 0.1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 38.08 kDa |
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Background
Biglycan, also known as PG I, is a secreted chondroitin/dermatan sulfate proteoglycan in the small leucine-rich proteoglycan (SLRP) family.The protein is plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, It may contribute to atherosclerosis and aortic valve stenosis in human patients.
Product information
| Synonym | BGN; DSPG1; MRLS; PG-S1; PGI; SEMDX; SLRR1A; biglycan |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
