Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein (RP00519LQ)

Overview

Product name	Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein
Catalog No.	RP00519LQ
Description	Recombinant Human CEACAM5/CEA/CD66e (145-322) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Pro145-Pro322) of Human CEACAM5/CD66e (145-322) (Accession #P06731-1) fused with a C-His tag at the C-terminus.
Purity	> 95% by SDS-PAGE；> 95% by HPLC
Endotoxin	< 1 EU/μg of the protein by LAL method
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Species	Human
Calculated MW	20.66 kDa

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Product information

Synonym	CEACAM-5; CD66e; CEA; Carcinoembryonic; CEACD66e
Expression Host	HEK293 cells
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.