Overview
| Product name | Recombinant Human CTSA Protein |
|---|
| Catalog No. | RP03198LQ |
|---|
| Description | Recombinant Human CTSA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala29-Tyr480) of human CTSA (Accession #NP_000299.2) fused with His tag at the C-terminus. |
|---|
| Purity | > 95% by SDS-PAGE. |
|---|
| Endotoxin | < 1.0 EU/μg of the protein by LAL method. |
|---|
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
|---|
| Species | Human |
|---|
| Calculated MW | 52.2 kDa |
|---|
Background
Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
Product information
| Synonym | Lysosomal protective protein; CTSA; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
