Overview
| Product name | Recombinant Human CXC-chemokine receptor 1/CXCR1 Protein |
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| Catalog No. | RP01933 |
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| Description | Recombinant Recombinant Human CXC-chemokine receptor 1/CXCR1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys39) of Human CXC-chemokine receptor 1/CXCR1 (Accession #NP_000625.1) fused with hFc tag at the C-terminus. |
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | <0.01EU/ug of the protein by LAL method |
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| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
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| Species | Human |
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| Calculated MW | 30.47 kDa |
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Background
Human CXC-chemokine receptor 1/CXCR1，Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor .Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Product information
| Synonym | CXCR1; CMKAR1; IL8RA; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CD181 |
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| Expression Host | HEK293 cells |
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| Tag | C-hFc |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
