Recombinant Human Calcitonin/CALCA Protein (RP01728)

Overview

Product name	Recombinant Human Calcitonin/CALCA Protein
Catalog No.	RP01728
Description	Recombinant Human Calcitonin/CALCA Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala26-Asn141) of human Calcitonin/CALCA (Accession #NP_001029124.1) fused with and a 6×His tag at the C-terminus.
Endotoxin	< 1EU/μg
Formulation	Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Species	Human
Calculated MW	13.64 kDa

This protein is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Product information

Synonym	CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I; CGRP-alpha; CALCA
Expression Host	HEK293 cells
Tag	C-6His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.