제품 > 재조합 단백질

Recombinant Human Calmodulin-1/CALM1 Protein (RP02931)

Datasheet

Overview

Product nameRecombinant Human Calmodulin-1/CALM1 Protein
Catalog No.RP02931
DescriptionRecombinant Human Calmodulin-1/CALM1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Lys149) of human Calmodulin-1/CALM1 (Accession #NP_001316851.1) fused with no additional amino acid.
Purity> 95% as determined by SDS-PAGE.
Endotoxin<1EU/μg
FormulationLyophilized from a 0.22 μm filtered solution of 50mM NH4HCO3, pH 8.0.
SpeciesHuman
Calculated MW16.8 kDa
Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.
SynonymCALM1; CALML2; CAMI; CPVT4; DD132; LQT14; PHKD; caM; CAMI; CPVT4; DD132; LQT14; PHKD; caM
Expression HostE. coli
TagNo tag
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

용량을 선택하세요
문의하기