Overview
| Product name | Recombinant Human DLL3 Protein |
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| Catalog No. | RP02041 |
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| Description | Recombinant Human CD40L/CD154 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala27-Arg491) of human DLL3 (Accession #Q9NYJ7) fused with a 6xHis, Flag tag at the N-terminus. |
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| Bio-Activity | Immobilized human DLL3 at 0.1 μg/mL (100 μL/well), dose response curve for Anti-Human DLL3 Ab with the EC50 of 10.53 ng/mL determined by ELISA.
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | < 0.1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, 200 mM Arginine, pH 7.4. Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 50.4 kDa |
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Background
Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene.Two transcript variants encoding distinct isoforms have been identified for this gene.Mutations in this gene cause the autosomal recessive genetic disorder Jarcho-Levin syndrome.Expression of the gene occurs in Neuroendocrine tumors, which has been targeted as a potential pathway for treatment.
Product information
| Synonym | Delta-like protein 3; SCDO1; DLL3 |
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| Expression Host | HEK293 cells |
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| Tag | N-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
