Overview
| Product name | Recombinant Human Follicle Stimulating Hormone (FSH) (CGA&FSHB) Protein |
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| Catalog No. | RP01695 |
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| Description | Recombinant Human Follicle Stimulating Hormone (FSH)（CGA&FSHB） Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala 25-Ser116＆Asn19-Glu129) of human Follicle Stimulating Hormone (FSH)（CGA&FSHB） (Accession #NP_000726.1＆NP_000501.1) fused with and a 6×His tag at the C-terminus(CGA). |
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| Purity | > 97% by SDS-PAGE. |
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| Endotoxin | <0.1EU/μg |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 11.03 (CGA) kDa, 12.49 (FSHB) kDa |
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Background
Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. FSH plays an essential role in processes involved in human reproduction, including spermatogenesis and the ovarian cycle. FSHB represents a conservative vertebrate gene with a unique function and it is located in a structurally stable gene-poor region. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) and follicle stimulating hormone receptor (FSHR) genes might disturb normal spermatogenesis and affect male reproductive ability. The FSHB -211G>T genotype is a key determinant in the regulation of gonadotropins in different reproductive-endocrine pathopyhsiologies.
Product information
| Synonym | HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; CG-ALPHA&HH24，CGA&FSHB；Follicle Stimulating Hormone (FSH)（CGA&FSHB） |
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| Expression Host | HEK293 cells |
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| Tag | C-His(CGA)&No tag(SHB) |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
