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Recombinant Human IGFBP-7 Protein (RP02738)

Bioactivityvalidated

Datasheet

Overview

Product nameRecombinant Human IGFBP-7 Protein
Catalog No.RP02738
DescriptionRecombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal.;It contains Asp30-Leu282
Bio-ActivityMeasured by its binding ability in a functional ELISA. Immobilized human IGFBP7 (Catalog: RP02738) at 2 μg/mL (100 μL/well) can bind human CD93 (Catalog: RP00164) with a linear range of 0.17-290.4 ng/mL.
Purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
EndotoxinLess than 1EU per μg by the LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
SpeciesHuman
Calculated MW27.02 kDa
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
SynonymIGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF ; IGFBP7; igfbp7
Expression HostHEK293 cells
TagN-His
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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