Overview
| Product name | Recombinant Human IL-10RA/CD210 Protein |
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| Catalog No. | RP01648 |
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| Description | Recombinant Human IL-10RA/CD210 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His22-Asn235) of human IL-10 R alpha (Accession #NP_001549.2) fused with and a RaFc tag at the C-terminus. |
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| Bio-Activity | Measured by its binding ability in a functional ELISA.Immobilized Human IL10 (Catalog: RP00093) at 2 μg/mL (100 μL/well) can bind Human IL10RA (Catalog: RP01648) with a linear range of 0.1-2.9 ng/mL.
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| Purity | > 92% by SDS-PAGE. |
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| Endotoxin | <0.1EU/μg |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 50.03 kDa |
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Background
IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other, not protein-coding have been found for this gene. CD210 belongs to the type II cytokine receptor family. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines.
Product information
| Synonym | CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1; IL10RA |
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| Expression Host | HEK293 cells |
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| Tag | C-Rabbit Fc |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
