Overview
| Product name | Recombinant Human IL-17A&IL-17F Protein |
|---|
| Catalog No. | RP02627 |
|---|
| Description | Recombinant Human IL-17A&IL-17F Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Ala155)&(Arg31-Gln163) of Human IL-17A&IL-17F (Accession #) fused with His tag at the C-terminal. |
|---|
| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
|---|
| Endotoxin | Less than 1EU per μg by the LAL method. |
|---|
| Species | Human |
|---|
| Calculated MW | 15.1 kDa (IL-17A), 15.7 kDa (IL-17F) |
|---|
Background
Interleukin?17A (IL?17A), also known as CTLA?8, is a 15?20 kDa glycosylated cytokine that plays an important role in anti?microbial and chronic inflammation. The six IL?17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Product information
| Synonym | IL-17A; Interleukin-17A; CTLA-8; IL-17; IL-17F; IL24; ML-1; Interleukin-17F |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
