Overview
| Product name | Recombinant Human Integrin alpha V beta3 (ITGB3＆ITGAV) Protein |
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| Catalog No. | RP01918 |
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| Description | Recombinant Human Integrin alpha V beta3 (ITGB3＆ITGAV) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human ITGB3 (Accession #NP_000203.2) fused with His tag at the C-terminus and (Phe31-Val992) of Human ITGAV (Accession #NP_002201.1)fused with His tag at the C-terminus. |
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| Endotoxin | <0.1EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 77.71 kDa(ITGB3), 111.94 kDa(ITGAV) |
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Background
Integrin beta-3 & alpha-V/ITGB3/ITGAV) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
Product information
| Synonym | ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61 & ITGAV，ITGAV; MSK8; VNRA; VTNR，Integrin alpha-V; Vitronectin receptor subunit alpha; CD51; Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain |
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| Expression Host | HEK293 cells |
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| Tag | C-His＆C-Flag |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
