Overview
| Product name | Recombinant Human LRG1 Protein |
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| Catalog No. | RP02953 |
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| Description | Recombinant Human LRG1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val36-Gln347) of human LRG1 (Accession #NP_443204.1) fused with a 6×His tag at the C-terminus. |
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| Bio-Activity | Immobilized Human LRG1, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-LRG1 Antibody, hFc Tag with the EC50 of 13.8ng/ml determined by ELISA.
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| Purity | > 95% as determined by HPLC |
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| Endotoxin | <1EU/μg |
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| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 35.4 kDa |
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Background
Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular complications of diabetes mellitus that is characterized by proteinuria and glomerular structural changes. LRG1 is a novel pro-angiogenic factors involved in the abnormal angiogenesis and renal fibrosis in DN.
Product information
| Synonym | LRG1; HMFT1766; LRG |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
