Overview
| Product name | Recombinant Human LRRC15/LIB Protein |
|---|
| Catalog No. | RP02705 |
|---|
| Description | Recombinant Human LRRC15/LIB Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.；It contains Tyr22-Gly538. |
|---|
| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
|---|
| Endotoxin | Less than 1EU per μg by the LAL method. |
|---|
| Species | Human |
|---|
| Calculated MW | 60.7 kDa |
|---|
Background
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.? LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.
Product information
| Synonym | LIB; LRRC15 |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His&Avi |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
