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Recombinant Human Oncostatin-M/OSM Protein (RP00054)

Bioactivityvalidated

Datasheet

Overview

Product nameRecombinant Human Oncostatin-M/OSM Protein
Catalog No.RP00054
DescriptionRecombinant Human Oncostatin-M/OSM Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala26-Arg221) of human Oncostatin-M/OSM (Accession #NP_065391.1).
Bio-ActivityMeasured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.8-3.2 ng/mL, corresponding to a specific activity of 3.12×105-1.25×106units/mg.
Purity> 95% by SDS-PAGE.
Endotoxin< 0.01 EU/μg of the protein by LAL method.
FormulationLyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, 5% glycerol, pH 7.4.Contact us for customized product form or formulation.
SpeciesHuman
Calculated MW22.15 kDa
This protein is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family. The preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells.
SynonymOSM; oncostatin-M
Expression HostE. coli
TagNo tag
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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16 Sep 2024-20 Dec 2024 on sale

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