Overview
Product name | Recombinant Human PRCP Protein |
---|
Catalog No. | RP03204LQ |
---|
Description | Recombinant Human PRCP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu22-His496) of Human PRCP (Accession #NP_005031.1) fused with 6×His tag at the C-terminus. |
---|
Purity | > 95% by SDS-PAGE. |
---|
Endotoxin | < 1 EU/μg of the protein by LAL method. |
---|
Formulation | Supplied as a 0.2 μm filtered solution of 20mM NaAc-HAc, 150mM NaCl, 10% Glycerol, pH4.5. |
---|
Species | Human |
---|
Calculated MW | 54.5 KDa |
---|
Background
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Product information
Synonym | Lysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP |
---|
Expression Host | HEK293 cells |
---|
Tag | C-His |
---|
Swiss-Prot | |
---|
Gene ID | |
---|
Usage guide
Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
---|
* For research use only. Not for therapeutic or diagnostic purposes.