Overview
| Product name | Recombinant Human Siglec-4a/MAG Protein |
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| Catalog No. | RP00424 |
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| Description | Recombinant Human Siglec-4a/MAG Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Gly20-Pro516) of human MAG/Siglec-4a (Accession #P20916) fused with a 6×His tag at the C-terminus. |
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | < 1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH7.2.Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 55.7 kDa |
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Background
This protein is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Product information
| Synonym | GMA; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75; MAG; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75 |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
