Overview
Product name | Recombinant Human TYRO3 Protein |
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Catalog No. | RP00203 |
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Description | Recombinant Human TYRO3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala41-Ser428) of human Tyro3/Dtk (Accession #NP_006284.2) fused with an Fc, 6×His tag at the C-terminus. |
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Bio-Activity | Measured by its binding ability in a functional ELISA. Immobilized Human Gas6 at 2 μg/mL (100 μL/well) can bind Human TYRO3 with a linear range of 0.1-5.6 ng/mL.
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Purity | > 95% by SDS-PAGE. |
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Endotoxin | < 0.1 EU/μg of the protein by LAL method. |
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Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
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Species | Human |
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Calculated MW | 68.32 kDa |
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Background
TYRO3, also known as Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken c-Eyk) constitute a new receptor tyrosine kinase subfamily. TYRO3 protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. TYRO3 has also been identified as a cell entry factor for Ebola and Marburg viruses.
Product information
Synonym | BYK; Dtk; Etk-2; RSE; Rek; Sky; Tif; TYRO3; Dtk; Etk-2; RSE; Rek; Sky; Tif |
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Expression Host | HEK293 cells |
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Tag | C-hFc&His |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.