Overview
| Product name | Recombinant Human VSIG2 Protein |
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| Catalog No. | RP02170 |
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| Description | Recombinant Human VSIG2 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Val24-Ala243) of human VSIG2 (Accession #Q96IQ7) fused with a 6xHis tag at the C- terminus. |
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | < 1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 24.2 kDa |
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Background
V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains, in several T-cell receptors such as CD2 (Cluster of Differentiation 2), CD4, CD80, and CD86, in myelin membrane adhesion molecules, in junction adhesion molecules (JAM), in tyrosine-protein kinase receptors, and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot, and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.
Product information
| Synonym | 2210413P10Rik; CTH; CTXL; VSIG2 |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
