Overview
| Product name | Recombinant Mouse Alpha-Synuclein/SNCA Protein |
|---|
| Catalog No. | RP00700 |
|---|
| Description | Recombinant Mouse Alpha-Synuclein/SNCA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Ala140) of mouse SNCA/Alpha-Synuclein (Accession #O55042). |
|---|
| Purity | > 95% by SDS-PAGE. |
|---|
| Endotoxin | < 1 EU/μg |
|---|
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. |
|---|
| Species | Mouse |
|---|
| Calculated MW | 14.49 kDa |
|---|
Background
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB).
Product information
| Synonym | Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloidprecursor; NACP; Snca |
|---|
| Expression Host | E. coli |
|---|
| Tag | No tag |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
