Overview
| Product name | Recombinant Mouse CLEC9A/CD370 Protein |
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| Catalog No. | RP02779LQ |
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| Description | Recombinant Mouse CLEC9A/CD370 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys57-Ile264) of mouse CLEC9A/CD370 (Accession #NP_001192292.1) fused with a hFc tag at the C-terminus. |
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| Purity | > 95% as determined by HPLC |
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| Endotoxin | <1EU/μg |
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| Formulation | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. |
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| Species | Mouse |
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| Calculated MW | 50.9 kDa |
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Background
CLEC9A expression was significantly higher in psoriatic skin compared with healthy donor. In psoriatic skin and PsA ST, CLEC9A() cells were in close proximity to TUNEL() cells. SF CLEC9A levels were significantly lower compared with paired PsA serum. Adalimumab treatment did not affect CLEC9A serum level and skin expression. The downregulation of synovial CLEC9A might be associated with a novel mechanism by which anti-TNF therapy might reduce CD8-mediated inflammation in PsA patients.
Product information
| Synonym | CD370; CLEC9A; 9830005G06Rik; DNGR-1; HEEE9341; UNQ9341 |
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| Expression Host | HEK293 cells |
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| Tag | C-hFc |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
