Overview
| Product name | Recombinant Mouse CXCL13/BLC Protein |
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| Catalog No. | RP02941LQ |
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| Description | Recombinant Mouse CXCL13/BLC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile22-Ala109) of mouse CXCL13/BLC (Accession #NP_061354.1) fused with 6×His tag at the N-terminus. |
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| Purity | > 95% as determined by HPLC. |
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| Endotoxin | <1EU/μg |
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| Formulation | Supplied as a 0.22 μm filtered solution in 50mM Tris, 500mM NaCl, pH 7.5. |
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| Species | Mouse |
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| Calculated MW | 11.7 kDa |
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Background
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
Product information
| Synonym | ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13 |
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| Expression Host | HEK293 cells |
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| Tag | N-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
