Overview
| Product name | Recombinant Mouse GFR alpha-like/GFRAL Protein |
|---|
| Catalog No. | RP02212 |
|---|
| Description | Recombinant Mouse GFR alpha-like/GFRAL Protein is produced by mammalian expression system. The target protein is expressed with sequence (Gln20-Glu350) of Mouse GFR alpha-like/GFRAL (Accession #) fused with a His and Avi tag at the N-terminal. . |
|---|
| Purity | > 95% as determined by Tris-Bis PAGE.> 95% as determined by HPLC |
|---|
| Endotoxin | < 1 EU per μg by the LAL method. |
|---|
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
|---|
| Species | Mouse |
|---|
| Calculated MW | 40.1 kDa |
|---|
Background
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses
Product information
| Synonym | GFR alpha-like; GFRAL; GRAL; C6orf144; Gfral |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | N-His&Avi |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
