Overview
| Product name | Recombinant Mouse GPVI Protein |
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| Catalog No. | RP02783LQ |
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| Description | Recombinant Mouse GPVI Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln22-Lys265) of mouse GPVI (Accession #NP_001156486.1) fused with a 6×His tag at the C-terminus. |
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| Purity | > 95% as determined by HPLC |
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| Endotoxin | <1EU/μg |
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| Formulation | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. |
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| Species | Mouse |
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| Calculated MW | 28 kDa |
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Background
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.
Product information
| Synonym | GPVI; Gp6; Glycoprotein 6; MGC138168 |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
