Overview
Product name | Recombinant Mouse Galectin-9/LGALS9 Protein |
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Catalog No. | RP02002LQ |
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Description | Recombinant Mouse Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus. |
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Purity | > 90 % as determined by SDS-PAGE |
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Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
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Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5Contact us for customized product form or formulation. |
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Species | Mouse |
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Calculated MW | 62.8 kDa |
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Background
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Product information
Synonym | Galectin-9; Lgals9; Gal-9 |
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Expression Host | E. coli |
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Tag | N-GST |
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Swiss-Prot | |
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Gene ID | |
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Usage guide
Storage | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.