Overview
| Product name | Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein |
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| Catalog No. | RP02656 |
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| Description | Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from Expi293 with His tag at the C-terminal.；It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail. |
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| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
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| Endotoxin | Less than 1EU per μg by the LAL method. |
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| Species | Mouse |
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| Calculated MW | 111.6(ITGAV) & 76.6(ITGB8) kDa |
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Background
Deletions of the genes encoding the integrin αVβ8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFβ activation.
Product information
| Synonym | Integrin alpha V beta 8；ITGAV&ITGB8 |
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| Expression Host | HEK293 cells |
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| Tag | C-His |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
