Overview
| Product name | Recombinant Mouse PDGF-AA Protein |
|---|
| Catalog No. | RP03145 |
|---|
| Description | Recombinant Mouse PDGF-AA Protein is produced by Pichia expression system. The target protein is expressed with sequence (Ser87-Arg196) of Mouse PDGF-AA (Accession #NP_032834.1) fused with a 6×His tag at the N-terminus. |
|---|
| Purity | > 95% by SDS-PAGE. |
|---|
| Endotoxin | Please contact us for more information. |
|---|
| Formulation | Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% CAN. Contact us for customized product form or formulation. |
|---|
| Species | Mouse |
|---|
| Calculated MW | 14.5 kDa. |
|---|
Background
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
Product information
| Synonym | PDGF1; PDGF-A; PDGFA |
|---|
| Expression Host | Pichia |
|---|
| Tag | N-His |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
