Overview
| Product name | Recombinant Mouse PDGFR-alpha/CD140a Protein |
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| Catalog No. | RP00718 |
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| Description | Recombinant Mouse PDGFR-alpha/CD140a Protein is produced by Human cells expression system. The target protein is expressed with sequence (Leu25-Glu524) of mouse PDGFR-alpha/CD140a (Accession #P26618) fused with an Fc tag at the C-terminus. |
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| Purity | > 95% by SDS-PAGE. |
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| Endotoxin | < 1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. |
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| Species | Mouse |
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| Calculated MW | 83.2 kDa |
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Background
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of theplatelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which formeither homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomericforms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- α and - β . These two receptorisoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, #NAMEsignaling has been linked to a number of proliferative disorders.
Product information
| Synonym | Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derivedgrowth factor receptor; CD140 antigen-like family member A; Platelet-derived growth factor alphareceptor; CD140a; PDGFRA |
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| Expression Host | HEK293 cells |
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| Tag | C-Fc |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
