Overview
| Product name | Recombinant Mouse TNFRSF18/GITR/CD357 Protein |
|---|
| Catalog No. | RP02678 |
|---|
| Description | Recombinant Mouse TNFRSF18/GITR/CD357 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser22-His153) of mouse TNFRSF18/GITR/CD357 (Accession #Q8C4K3) fused with His tag at the C-terminus. |
|---|
| Purity | > 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC |
|---|
| Endotoxin | Less than 1EU per μg by the LAL method. |
|---|
| Species | Mouse |
|---|
| Calculated MW | 15.2 kDa |
|---|
Background
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Product information
| Synonym | CD357; GITR; GITR-D; TNFRSF18; AITR |
|---|
| Expression Host | HEK293 cells |
|---|
| Tag | C-His |
|---|
| Swiss-Prot | |
|---|
| Gene ID | |
|---|
Usage guide
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
|---|
| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
|---|
* For research use only. Not for therapeutic or diagnostic purposes.
