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Human CD52 Monoclonal Antibody (YR0012)

Datasheet

ABclonal:Flow CytoMetry - Human CD52 Monoclonal Antibody (YR0012)

Detection of CD52 in Human PBMCs cell line by Flow Cytometry. Human PBMCs cell line was stained with Biotinylated Human Anti-Human CD52(Alemtuzumab Biosimilar) Monoclonal Antibody followed by APC conjugated NeutrAvidin Secondary Antibody, or unstained cells (open blue histogram).

Basic Information

CloneAlemtuzumab Biosimilar
Molecular Weight150 kDa
Endotoxin<1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Sterility0.2 μm filtration
Aggregation<5% Determined by SECP
Purity>95% Determined by SDS-PAGE
ProductionPurified from cell culture supernatant in an animal-free facility
PurificationProtein A or G purification
Storage2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Alemtuzumab Biosimilar uses the same protein sequences as the therapeutic antibody alemtuzumab.Alemtuzumab is a medication used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. In CLL, it has been used as both a first line and second line treatment. In MS it is generally only recommended if other treatments have not worked. It is given by injection into a vein.It is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction.
IsotypeHuman IgG1 kappa
ImmunogenHuman CD52
RecommendedIsotype Control(s)In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Recommended Dilution Buffer1×PBS pH 7.0
ABclonal:Flow CytoMetry - Human CD52 Monoclonal Antibody (YR0012)}

Flow CytoMetry - Human CD52 Monoclonal Antibody (YR0012)

Detection of CD52 in Human PBMCs cell line by Flow Cytometry. Human PBMCs cell line was stained with Biotinylated Human Anti-Human CD52(Alemtuzumab Biosimilar) Monoclonal Antibody followed by APC conjugated NeutrAvidin Secondary Antibody, or unstained cells (open blue histogram).

* For research use only. Not for therapeutic or diagnostic purposes.