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Pseudouridine / 5-ribosyluracil Rabbit pAb (A18872)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Species independent

ABclonal:Dot Blot - Pseudouridine / 5-ribosyluracil Rabbit pAb (A18872)

Dot-blot analysis of all sorts of chemical compounds using Pseudouridine / 5-ribosyluracil antibody (A18872) at 1:5000/1:10000 dilution

Overview

Product namePseudouridine / 5-ribosyluracil Rabbit pAb
Catalog No.A18872
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
Pseudouridine is the most abundant post-transcriptional RNA modification, which presents mostly in non-coding RNAs such as tRNA, rRNA, snRNA and snoRNA. Pseudouridine impacts various aspects of RNA biology, conferring distinct structural and functional properties to the RNA molecules that it decorates.? It is also reported that pseudouridine has been found in mRNA in both yeast and human by sequencing analysis. Replacing uridine to pseudouridine enhances structural stability of RNA, and is expected to affect rRNA processing, translation and pre-mRNA splicing. Also, aberrant pseudouridylation contributes to a variety of human diseases, including cancer and genetic disorders. Dysregulation of the pseudouridine epitranscriptome can arise from mutations and abnormal expression of pseudouridylation machinery, impacting protein translation and other cellular processes.
ImmunogenChemical compounds corresponding to Pseudouridine / 5-ribosyluracil / Y.
SequenceEmail for sequence
Gene ID
Swiss Prot
Synonyms
Calculated MW
Observed MWRefer to figures
ReactivitySpecies independent
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • DB 1:3000 - 1:10000
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Key application
Positive samples
Cellular location

Documents

Certificate of Compliance

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Lot number

    ABclonal:Dot Blot - Pseudouridine / 5-ribosyluracil Rabbit pAb (A18872)}

    Dot Blot - Pseudouridine / 5-ribosyluracil Rabbit pAb (A18872)

    Dot-blot analysis of all sorts of chemical compounds using Pseudouridine / 5-ribosyluracil antibody (A18872) at 1:5000/1:10000 dilution

    * For research use only. Not for therapeutic or diagnostic purposes.