Overview
| Product name | Biotinylated Recombinant Human Angiopoietin-like 3/ANGPTL3 (17-219) Protein |
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| Catalog No. | RP02273B |
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| Description | Biotinylated Recombinant HumanAngiopoietin-like 3/ANGPTL3(17-219) Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser17-Lys219) of Human Angiopoietin-like 3/ANGPTL3 fused with His tag and Avi tag at the C-terminus. |
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| Purity | > 95% by Tris-Bis PAGE |
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| Endotoxin | < 1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation. |
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| Species | Human |
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| Calculated MW | 26.6 kDa |
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Background
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.
Product information
| Synonym | ANG-5; ANGPT5; ANL3; FHBL2; ANGPTL3; ANGPT5; ANL3; FHBL2 |
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| Expression Host | HEK293 cells |
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| Tag | C-His&Avi |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
