Overview
| Product name | Biotinylated Recombinant Human IL-17RA/CD217 Protein |
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| Catalog No. | RP02423B |
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| Description | Biotinylated Recombinant Human IL-17RA/CD217 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Leu33-Trp320) of Human IL-17RA fused with a His tag and Avi tag at the C-terminal. |
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| Purity | > 95% by Tris-Bis PAGE;> 92% by SEC-HPLC |
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| Endotoxin | < 1 EU/μg of the protein by LAL method. |
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| Formulation | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
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| Species | Human |
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| Calculated MW | 36.4 kDa |
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Background
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
Product information
| Synonym | CANDF5; CD217; CDw217; IL-17RA; IL17R; IMD51; hIL-17R; IL17RA; CD217; CDw217; IL-17RA; IL17R; IMD51; hIL-17R |
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| Expression Host | HEK293 cells |
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| Tag | C-His&Avi |
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| Swiss-Prot | |
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| Gene ID | |
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Usage guide
| Storage | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
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| Reconstitution | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
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* For research use only. Not for therapeutic or diagnostic purposes.
