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Biotinylated Recombinant Human LAG-3/CD223 Protein (RP02553)

Publication (1) Datasheet

Overview

Product nameBiotinylated Recombinant Human LAG-3/CD223 Protein
Catalog No.RP02553
DescriptionRecombinant Biotinylated Human LAG3/CD223 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.;It contains Leu23-Gly434.
Purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
EndotoxinLess than 1EU per μg by the LAL method.
SpeciesHuman
LAG-3, is a protein which in humans is encoded by the LAG3 gene, which is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders.
SynonymCD223; FDC; LAG3; LAG-3; sLAG-3
Expression HostHEK293 cells
TagC-His&Avi
Swiss-Prot
Gene ID
StorageStore at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
ReconstitutionCentrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.

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