Biotinylated Recombinant Human Siglec-3/CD33 Protein (RP00555BLQ)

Overview

Product name	Biotinylated Recombinant Human Siglec-3/CD33 Protein
Catalog No.	RP00555BLQ
Description	Biotinylated Recombinant Human Siglec-3/CD33 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp18-His259) of Human Siglec-3/CD33 (Accession #P20138-1) fused with a C-His&Avi tag at the C-terminus.
Purity	> 95% by SDS-PAGE；> 90% by HPLC
Endotoxin	< 1 EU/μg of the protein by LAL method
Formulation	Supplied as 0.22 μm filtered solution in 50 mM MES, 500 mM NaCl, 200 mM L-arginine (pH 7.4).
Species	Human
Calculated MW	29.6 kDa

Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.

Product information

Synonym	CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67
Expression Host	HEK293 cells
Tag	C-His&Avi
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.