Recombinant Human IL-17RB Protein (RP02679)

Overview

Product name	Recombinant Human IL-17RB Protein
Catalog No.	RP02679
Description	Recombinant Human IL-17RB Protein is expressed from Expi293 with His tag at the C-terminal.；It contains Arg18-Per292.
Purity	> 95% as determined by Tris-Bis PAGE；> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Species	Human
Calculated MW	31.4 kDa

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.

Product information

Synonym	IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB
Expression Host	HEK293 cells
Tag	C-His
Swiss-Prot
Gene ID

Usage guide

Storage	Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution	Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

* For research use only. Not for therapeutic or diagnostic purposes.